UniProt P00940
Triose phosphate isomerase (P00940)
Triose phosphate isomerase (UniProt P00940), EC 5.3.1.1: 34 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00940
- Protein
- Triose phosphate isomerase
- EC
- 5.3.1.1
- Experimental structures
- 34
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
35 records of P00940 in the MolNFT archive: 34 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1SPQ | Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase | x-ray diffraction | A, B | — | — |
| 1SPQ | Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase | x-ray diffraction | A, B | — | — |
| 1SQ7 | Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase | x-ray diffraction | A, B | — | — |
| 1SQ7 | Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase | x-ray diffraction | A, B | — | — |
| 1SSD | Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase | x-ray diffraction | A, B | — | — |
| 1SSD | Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase | x-ray diffraction | A, B | — | — |
| 1SSG | Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase | x-ray diffraction | A, B | — | — |
| 1SSG | Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase | x-ray diffraction | A, B | — | — |
| 1SU5 | Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase | x-ray diffraction | A, B | — | — |
| 1SU5 | Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase | x-ray diffraction | A, B | — | — |
| 1SW0 | Triosephosphate isomerase from Gallus gallus, loop 6 hinge mutant K174L, T175W | x-ray diffraction | A, B | — | — |
| 1SW0 | Triosephosphate isomerase from gallus gallus, loop 6 hinge mutant K174L, T175W | x-ray diffraction | A, B | — | — |
| 1SW3 | Triosephosphate isomerase from Gallus gallus, loop 6 mutant T175V | x-ray diffraction | A, B | — | — |
| 1SW3 | Triosephosphate isomerase from gallus gallus, loop 6 mutant T175V | x-ray diffraction | A, B | — | — |
| 1SW7 | Triosephosphate isomerase from Gallus gallus, loop 6 mutant K174N, T175S, A176S | x-ray diffraction | A, B | — | — |
| 1SW7 | Triosephosphate isomerase from gallus gallus, loop 6 mutant K174N, T175S, A176S | x-ray diffraction | A, B | — | — |
| 1TIM | Structure of triose phosphate isomerase from chicken muscle | x-ray diffraction | A, B | — | — |
| 1TIM | Structure of triose phosphate isomerase from chicken muscle | x-ray diffraction | A, B | — | — |
| 1TPB | Offset of a catalytic lesion by a bound water soluble | x-ray diffraction | 1, 2 | — | — |
| 1TPB | Offset of a catalytic lesion by a bound water soluble | x-ray diffraction | 1, 2 | — | — |
| 1TPC | Offset of a catalytic lesion by a bound water soluble | x-ray diffraction | 1, 2 | — | — |
| 1TPC | Offset of a catalytic lesion by a bound water soluble | x-ray diffraction | 1, 2 | — | — |
| 1TPH | 1.8 ångströms crystal structure of wild type chicken triosephosphate… | x-ray diffraction | 1, 2 | — | — |
| 1TPH | 1.8 ångströms crystal structure of wild type chicken triosephosphate… | x-ray diffraction | 1, 2 | — | — |
| 1TPU | S96P change is a second-site suppressor for H95N sluggish mutant triosephosphate isomerase | x-ray diffraction | A, B | — | — |
| 1TPU | S96P change is a second-site suppressor for H95N sluggish mutant triosephosphate isomerase | x-ray diffraction | A, B | — | — |
| 1TPV | S96P change is a second-site suppressor for H95N sluggish mutant triosephosphate isomerase | x-ray diffraction | A, B | — | — |
| 1TPV | S96P change is a second-site suppressor for H95N sluggish mutant triosephosphate isomerase | x-ray diffraction | A, B | — | — |
| 1TPW | Triosephosphate isomerase drinks water to keep healthy | x-ray diffraction | A, B | — | — |
| 1TPW | Triosephosphate isomerase drinks water to keep healthy | x-ray diffraction | A, B | — | — |
| 4P61 | Chicken triosephosphate isomerase with LOOP6 mutations, V167P and W168E. | x-ray diffraction | A, B | — | — |
| 4P61 | Chicken triosephosphate isomerase with LOOP6 mutations, V167P and W168E. | x-ray diffraction | A, B | — | — |
| 8TIM | Triose phosphate isomerase | x-ray diffraction | A, B | SO4 | 4 (best 0.68) |
| 8TIM | Triose phosphate isomerase | x-ray diffraction | A, B | SO4 | — |
| P00940 | AlphaFold monomer V2.0 prediction for triosephosphate isomerase (P00940) | predicted | A | — | 1 (best 0.43) |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 1TPB chain 1 against the predicted model P00940: TM-score 1.00, RMSD 0.24 Å
- 1TPB chain 1 against the predicted model P00940: TM-score 1.00, RMSD 0.24 Å
- 1SW3 chain A against the predicted model P00940: TM-score 1.00, RMSD 0.24 Å
- 1SW3 chain A against the predicted model P00940: TM-score 1.00, RMSD 0.24 Å
- 1TPC chain 1 against the predicted model P00940: TM-score 1.00, RMSD 0.25 Å
- 1TPC chain 1 against the predicted model P00940: TM-score 1.00, RMSD 0.25 Å
- 1TPH chain 1 against the predicted model P00940: TM-score 1.00, RMSD 0.25 Å
- 1TPH chain 1 against the predicted model P00940: TM-score 1.00, RMSD 0.25 Å
- 1TPV chain A against the predicted model P00940: TM-score 1.00, RMSD 0.26 Å
- 1TPV chain A against the predicted model P00940: TM-score 1.00, RMSD 0.26 Å
Elsewhere
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