UniProt P00888
Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive (P00888)
Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive (UniProt P00888), EC 2.5.1.54: 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 28 pockets. Binding sites, druggability and experiment…
- UniProt
- P00888
- Protein
- Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive
- EC
- 2.5.1.54
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 28 · 2 records with a druggable one
Structures
5 records of P00888 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6AGL | Molecular basis for feedback inhibition of tyrosine-regulated… | x-ray diffraction | A, B | — | 10 (best 0.66) |
| 6AGL | Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy… | x-ray diffraction | A, B | — | — |
| 6AGM | Molecular basis for feedback inhibition of tyrosine-regulated… | x-ray diffraction | A, B, C, D | TYR | 18 (best 0.69) |
| 6AGM | Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy… | x-ray diffraction | A, B, C, D | — | — |
| P00888 | AlphaFold monomer V2.0 prediction for phospho-2-dehydro-3-deoxyheptonate aldolase, tyr-sensitive… | predicted | A | — | — |
Ligands
- TYR · Tyrosine · in 1 record
Experiment against prediction
- 6AGL chain A against the predicted model P00888: TM-score 0.98, RMSD 1.06 Å
- 6AGL chain A against the predicted model P00888: TM-score 0.98, RMSD 1.06 Å
- 6AGL chain B against the predicted model P00888: TM-score 0.98, RMSD 1.06 Å
- 6AGL chain B against the predicted model P00888: TM-score 0.98, RMSD 1.06 Å
- 6AGM chain B against the predicted model P00888: TM-score 0.97, RMSD 1.28 Å
- 6AGM chain C against the predicted model P00888: TM-score 0.97, RMSD 1.28 Å
- 6AGM chain A against the predicted model P00888: TM-score 0.97, RMSD 1.29 Å
- 6AGM chain B against the predicted model P00888: TM-score 0.97, RMSD 1.28 Å
- 6AGM chain D against the predicted model P00888: TM-score 0.97, RMSD 1.34 Å
- 6AGM chain C against the predicted model P00888: TM-score 0.97, RMSD 1.28 Å
Elsewhere
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