UniProt P00856
ATP synthase protein 8 (P00856)
ATP synthase protein 8 (UniProt P00856): 49 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00856
- Protein
- ATP synthase protein 8
- Experimental structures
- 49
- Predicted models
- 1
- Pockets
- 14 · 8 records with a druggable one
Structures
50 records of P00856 in the MolNFT archive: 49 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6B2Z | Cryo-EM structure of the dimeric fo region of yeast mitochondrial ATP synthase | electron microscopy | A, L | — | — |
| 6B8H | Mosaic model of yeast mitochondrial ATP synthase monomer | electron microscopy | A, V | — | — |
| 6CP3 | Monomer yeast ATP synthase (F1Fo) reconstituted in nanodisc with inhibitor of oligomycin bound. | electron microscopy | 8 | — | — |
| 6CP3 | Monomer yeast ATP synthase (F1FO) reconstituted in nanodisc with inhibitor of oligomycin bound. | electron microscopy | 8 | — | — |
| 6CP5 | Monomer yeast ATP synthase fo reconstituted in nanodisc with inhibitor of oligomycin bound… | electron microscopy | 8 | — | — |
| 6CP6 | Monomer yeast ATP synthase (F1FO) reconstituted in nanodisc. | electron microscopy | 8 | — | — |
| 6CP7 | Monomer yeast ATP synthase fo reconstituted in nanodisc generated from masked refinement. | electron microscopy | 8 | — | — |
| 6WTD | Monomer yeast ATP synthase Fo reconstituted in nanodisc with inhibitor of Bedaquiline bound | electron microscopy | 8 | — | 5 (best 0.74) |
| 6WTD | Monomer yeast ATP synthase fo reconstituted in nanodisc with inhibitor of bedaquiline bound | electron microscopy | 8 | — | — |
| 7TJZ | Yeast ATP synthase state 1CATALYTIC(B) without exogenous ATP backbone model | electron microscopy | Z | — | — |
| 7TK0 | Yeast ATP synthase State 1catalytic(c) without exogenous ATP backbone model | electron microscopy | Z | — | — |
| 7TK1 | Yeast ATP synthase State 1catalytic(d) without exogenous ATP backbone model | electron microscopy | Z | — | 1 (best 0.65) |
| 7TK1 | Yeast ATP synthase state 1CATALYTIC(D) without exogenous ATP backbone model | electron microscopy | Z | — | — |
| 7TK2 | Yeast ATP synthase state 1BINDING(A) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TK4 | Yeast ATP synthase State 1binding(c) with 10 mM ATP backbone model | electron microscopy | Z | — | — |
| 7TK4 | Yeast ATP synthase state 1BINDING(C) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TK5 | Yeast ATP synthase state 1BINDING(D) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TK6 | Yeast ATP synthase State 1catalytic(a) with 10 mM ATP backbone model | electron microscopy | Z | — | 2 (best 0.67) |
| 7TK7 | Yeast ATP synthase state 1CATALYTIC(B) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TK8 | Yeast ATP synthase State 1catalytic(c) with 10 mM ATP backbone model | electron microscopy | Z | — | 1 (best 0.64) |
| 7TK8 | Yeast ATP synthase state 1CATALYTIC(C) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TK9 | Yeast ATP synthase State 1catalytic(d) with 10 mM ATP backbone model | electron microscopy | Z | — | 1 (best 0.59) |
| 7TK9 | Yeast ATP synthase state 1CATALYTIC(D) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKA | Yeast ATP synthase State 1catalytic(e) with 10 mM ATP backbone model | electron microscopy | Z | — | — |
| 7TKA | Yeast ATP synthase state 1CATALYTIC(E) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKB | Yeast ATP synthase State 1catalytic(f) with 10 mM ATP backbone model | electron microscopy | Z | — | — |
| 7TKB | Yeast ATP synthase state 1CATALYTIC(F) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKC | Yeast ATP synthase State 1catalytic(g) with 10 mM ATP backbone model | electron microscopy | Z | — | — |
| 7TKC | Yeast ATP synthase state 1CATALYTIC(G) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKD | Yeast ATP synthase state 1CATALYTIC(H) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKE | Yeast ATP synthase State 2binding(a) with 10 mM ATP backbone model | electron microscopy | Z | — | 1 (best 0.63) |
| 7TKE | Yeast ATP synthase state 2BINDING(A) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKF | Yeast ATP synthase State 2binding(b) with 10 mM ATP backbone model | electron microscopy | Z | — | — |
| 7TKF | Yeast ATP synthase state 2BINDING(B) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKG | Yeast ATP synthase state 2CATALYTIC(A) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKH | Yeast ATP synthase state 2CATALYTIC(B) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKI | Yeast ATP synthase state 2CATALYTIC(C) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKJ | Yeast ATP synthase State 2catalytic(d) with 10 mM ATP backbone model | electron microscopy | Z | — | — |
| 7TKJ | Yeast ATP synthase state 2CATALYTIC(D) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKK | Yeast ATP synthase state 2CATALYTIC(E) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKL | Yeast ATP synthase state 3BINDING(A) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKN | Yeast ATP synthase state 3BINDING(C) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKO | Yeast ATP synthase state 3CATALYTIC(A) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKP | Yeast ATP synthase state 3CATALYTIC(B) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKQ | Yeast ATP synthase State 3catalytic(c) with 10 mM ATP backbone model | electron microscopy | Z | — | 1 (best 0.59) |
| 7TKR | Yeast ATP synthase State 3catalytic(d) with 10 mM ATP backbone model | electron microscopy | Z | — | — |
| 7TKR | Yeast ATP synthase state 3CATALYTIC(D) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 7TKS | Yeast ATP synthase state 3CATALYTIC(E) with 10 mm ATP backbone model | electron microscopy | Z | — | — |
| 8F39 | Yeast ATP synthase in conformation-2, at pH 6 | electron microscopy | 8 | — | 2 (best 0.74) |
| P00856 | AlphaFold monomer V2.0 prediction for ATP synthase protein 8 (P00856) | predicted | A | — | — |
Experiment against prediction
- 6CP5 chain 8 against the predicted model P00856: TM-score 0.87, RMSD 0.78 Å
- 6CP7 chain 8 against the predicted model P00856: TM-score 0.87, RMSD 0.81 Å
- 6CP3 chain 8 against the predicted model P00856: TM-score 0.86, RMSD 0.81 Å
- 6CP3 chain 8 against the predicted model P00856: TM-score 0.86, RMSD 0.81 Å
- 6CP6 chain 8 against the predicted model P00856: TM-score 0.86, RMSD 0.81 Å
- 7TK9 chain Z against the predicted model P00856: TM-score 0.82, RMSD 1.26 Å
- 7TK9 chain Z against the predicted model P00856: TM-score 0.82, RMSD 1.26 Å
- 7TKI chain Z against the predicted model P00856: TM-score 0.81, RMSD 1.26 Å
- 7TKJ chain Z against the predicted model P00856: TM-score 0.81, RMSD 1.30 Å
- 7TKJ chain Z against the predicted model P00856: TM-score 0.81, RMSD 1.30 Å
Elsewhere
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