UniProt P00817
Protein (inorganic pyrophosphatase) (P00817)
Protein (inorganic pyrophosphatase) (UniProt P00817), EC 3.6.1.1: 38 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P00817
- Protein
- Protein (inorganic pyrophosphatase)
- EC
- 3.6.1.1
- Experimental structures
- 38
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 6 · 1 record with a druggable one
Structures
39 records of P00817 in the MolNFT archive: 38 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 117E | The R78K and D117E active site variants of saccharomyces cerevisiae soluble inorganic… | x-ray diffraction | A, B | — | — |
| 117E | The R78K and D117E active site variants of saccharomyces cerevisiae soluble inorganic… | x-ray diffraction | A, B | — | — |
| 1E6A | Fluoride-inhibited substrate complex of Saccharomyces cerevisiae inorganic pyrophosphatase | x-ray diffraction | A, B | — | — |
| 1E6A | Fluoride-inhibited substrate complex of saccharomyces cerevisiae inorganic pyrophosphatase | x-ray diffraction | A, B | — | — |
| 1E9G | Structure of inorganic pyrophosphatase | x-ray diffraction | A, B | — | — |
| 1E9G | Structure of inorganic pyrophosphatase | x-ray diffraction | A, B | — | — |
| 1HUJ | Refined structure of yeast inorganic pyrophosphatase and its K61R mutant | x-ray diffraction | A, B | — | — |
| 1HUJ | Refined structure of yeast inorganic pyrophosphatase and its K61R mutant | x-ray diffraction | A, B | — | — |
| 1HUK | Refined structure of yeast inorganic pyrophosphatase and its K61R mutant | x-ray diffraction | A, B | — | — |
| 1HUK | Refined structure of yeast inorganic pyrophosphatase and its K61R mutant | x-ray diffraction | A, B | — | — |
| 1M38 | Structure of Inorganic Pyrophosphatase | x-ray diffraction | A, B | — | — |
| 1M38 | Structure of inorganic pyrophosphatase | x-ray diffraction | A, B | — | — |
| 1PYP | X-ray diffraction study of inorganic pyrophosphatase from BAKER,S yeast at the 3 ångströms… | x-ray diffraction | A, B | — | — |
| 1PYP | X-ray diffraction study of inorganic pyrophosphatase from BAKER,S yeast at the 3 ångströms… | x-ray diffraction | A, B | — | — |
| 1WGI | Structure of inorganic pyrophosphatase | x-ray diffraction | A, B | — | — |
| 1WGI | Structure of inorganic pyrophosphatase | x-ray diffraction | A, B | — | — |
| 1WGJ | Structure of inorganic pyrophosphatase | x-ray diffraction | A, B | — | — |
| 1WGJ | Structure of inorganic pyrophosphatase | x-ray diffraction | A, B | — | — |
| 1YPP | Acid anhydride hydrolase | x-ray diffraction | A, B | — | — |
| 1YPP | Acid anhydride hydrolase | x-ray diffraction | A, B | — | — |
| 2IHP | Yeast inorganic pyrophosphatase with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 2IHP | Yeast inorganic pyrophosphatase with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 2IK0 | Yeast inorganic pyrophosphatase variant E48D with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 2IK0 | Yeast inorganic pyrophosphatase variant E48D with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 2IK1 | Yeast inorganic pyrophosphatase variant Y93F with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 2IK1 | Yeast inorganic pyrophosphatase variant Y93F with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 2IK2 | Yeast inorganic pyrophosphatase variant D115E with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 2IK2 | Yeast inorganic pyrophosphatase variant D115E with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 2IK4 | Yeast inorganic pyrophosphatase variant D117E with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 2IK4 | Yeast inorganic pyrophosphatase variant D117E with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 2IK6 | Yeast inorganic pyrophosphatase variant D120E with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 2IK6 | Yeast inorganic pyrophosphatase variant D120E with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 2IK7 | Yeast inorganic pyrophosphatase variant D120N with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 2IK7 | Yeast inorganic pyrophosphatase variant D120N with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 2IK9 | Yeast inorganic pyrophosphatase variant D152E with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 2IK9 | Yeast inorganic pyrophosphatase variant D152E with magnesium and phosphate | x-ray diffraction | A, B | — | — |
| 8PRK | The R78K and D117E active site variants of saccharomyces cerevisiae soluble inorganic… | x-ray diffraction | A, B | MN, PO4 | 6 (best 0.66) |
| 8PRK | The R78K and D117E active site variants of saccharomyces cerevisiae soluble inorganic… | x-ray diffraction | A, B | MN, PO4 | — |
| P00817 | AlphaFold monomer V2.0 prediction for inorganic pyrophosphatase (P00817) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1M38 chain A against the predicted model P00817: TM-score 1.00, RMSD 0.20 Å
- 1M38 chain A against the predicted model P00817: TM-score 1.00, RMSD 0.20 Å
- 2IK6 chain B against the predicted model P00817: TM-score 1.00, RMSD 0.23 Å
- 2IK6 chain B against the predicted model P00817: TM-score 1.00, RMSD 0.23 Å
- 2IHP chain B against the predicted model P00817: TM-score 1.00, RMSD 0.23 Å
- 2IHP chain B against the predicted model P00817: TM-score 1.00, RMSD 0.23 Å
- 2IK1 chain B against the predicted model P00817: TM-score 1.00, RMSD 0.23 Å
- 2IK1 chain B against the predicted model P00817: TM-score 1.00, RMSD 0.23 Å
- 2IK2 chain B against the predicted model P00817: TM-score 1.00, RMSD 0.24 Å
- 2IK2 chain B against the predicted model P00817: TM-score 1.00, RMSD 0.24 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.