UniProt P00816
Cyanate hydratase (P00816)
Cyanate hydratase (UniProt P00816), EC 4.2.1.104: 19 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 60 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00816
- Protein
- Cyanate hydratase
- EC
- 4.2.1.104
- Experimental structures
- 19
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 60 · 3 records with a druggable one
Structures
20 records of P00816 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1DW9 | Structure of cyanase reveals that a novel dimeric and decameric arrangement of subunits is required… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 1DW9 | Structure of cyanase reveals that a novel dimeric and decameric arrangement of subunits is required… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 1DWK | Structure of cyanase with the di-anion oxalate bound at the enzyme active site | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 1DWK | Structure of cyanase with the di-anion oxalate bound at the enzyme active site | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2IU7 | Site directed mutagenesis of key residues involved in the catalytic mechanism of Cyanase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2IU7 | Site directed mutagenesis of key residues involved in the catalytic mechanism of cyanase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2IUO | Site Directed Mutagenesis of Key Residues Involved in the Catalytic Mechanism of Cyanase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2IUO | Site directed mutagenesis of key residues involved in the catalytic mechanism of cyanase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2IV1 | Site directed mutagenesis of key residues involved in the catalytic mechanism of cyanase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2IV1 | Site directed mutagenesis of key residues involved in the catalytic mechanism of cyanase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2IVB | Site directed mutagenesis of key residues involved in the catalytic mechanism of cyanase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2IVB | Site directed mutagenesis of key residues involved in the catalytic mechanism of cyanase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2IVG | Site directed mutagenesis of key residues involved in the catalytic mechanism of cyanase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2IVG | Site directed mutagenesis of key residues involved in the catalytic mechanism of cyanase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2IVQ | Site directed mutagenesis of key residues involved in the catalytic mechanism of cyanase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2IVQ | Site directed mutagenesis of key residues involved in the catalytic mechanism of cyanase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 8K6H | Crystal structure of e.coli cyanase complex with cyanate | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | SO4, 0NM | 20 (best 0.76) |
| 8K6S | Crystal structure of E.coli Cyanase complex with bicarbonate | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | SO4, CO3 | 20 (best 0.78) |
| 8K6X | Crystal structure of E.coli Cyanase complex with cyanate and bicarbonate | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | SO4, CO3, VQO | 20 (best 0.83) |
| P00816 | AlphaFold monomer V2.0 prediction for cyanate hydratase (P00816) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2IVG chain I against the predicted model P00816: TM-score 1.00, RMSD 0.24 Å
- 2IVG chain I against the predicted model P00816: TM-score 1.00, RMSD 0.24 Å
- 1DW9 chain F against the predicted model P00816: TM-score 1.00, RMSD 0.24 Å
- 1DW9 chain F against the predicted model P00816: TM-score 1.00, RMSD 0.24 Å
- 1DWK chain F against the predicted model P00816: TM-score 1.00, RMSD 0.24 Å
- 1DWK chain F against the predicted model P00816: TM-score 1.00, RMSD 0.24 Å
- 2IVG chain F against the predicted model P00816: TM-score 1.00, RMSD 0.25 Å
- 2IVG chain F against the predicted model P00816: TM-score 1.00, RMSD 0.25 Å
- 1DW9 chain B against the predicted model P00816: TM-score 1.00, RMSD 0.25 Å
- 1DW9 chain B against the predicted model P00816: TM-score 1.00, RMSD 0.25 Å
Elsewhere
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