UniProt P00757
Nerve growth factor (P00757)
Nerve growth factor (UniProt P00757), EC 3.4.21.35: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00757
- Protein
- Nerve growth factor
- EC
- 3.4.21.35
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 14 · 2 records with a druggable one
Structures
3 records of P00757 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1SGF | Crystal structure of 7S ngf: a complex of nerve growth factor with four binding proteins (serine… | x-ray diffraction | A, X | NAG, ZN | 13 (best 0.78) |
| 1SGF | Crystal structure of 7S ngf: a complex of nerve growth factor with four binding proteins (serine… | x-ray diffraction | A, X | — | — |
| P00757 | AlphaFold monomer V2.0 prediction for kallikrein 1-related peptidase- like B4 (P00757) | predicted | A | — | 1 (best 0.59) |
Ligands
Experiment against prediction
- 1SGF chain A against the predicted model P00757: TM-score 0.93, RMSD 1.78 Å
- 1SGF chain A against the predicted model P00757: TM-score 0.93, RMSD 1.78 Å
- 1SGF chain X against the predicted model P00757: TM-score 0.91, RMSD 1.91 Å
- 1SGF chain X against the predicted model P00757: TM-score 0.91, RMSD 1.91 Å
Elsewhere
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