UniProt P00729
Serine carboxypeptidase (P00729)
Serine carboxypeptidase (UniProt P00729), EC 3.4.16.5: 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00729
- Protein
- Serine carboxypeptidase
- EC
- 3.4.16.5
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 20 · 6 records with a druggable one
Structures
7 records of P00729 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1CPY | Site-directed mutagenesis on (serine) carboxypeptidase Y from yeast. the significance of thr 60 and… | x-ray diffraction | A | NAG | 2 (best 0.67) |
| 1CPY | Site-directed mutagenesis on (serine) carboxypeptidase Y from yeast. the significance of thr 60 and… | x-ray diffraction | A | NAG | 2 (best 0.67) |
| 1WPX | Crystal structure of carboxypeptidase Y inhibitor complexed with the cognate proteinase | x-ray diffraction | A | NAG, SO4 | 6 (best 0.76) |
| 1WPX | Crystal structure of carboxypeptidase Y inhibitor complexed with the cognate proteinase | x-ray diffraction | A | ACE, NAG, SO4 | 6 (best 0.76) |
| 1YSC | 2.8 ångströms structure of yeast serine carboxypeptidase | x-ray diffraction | A | NAG | 2 (best 0.65) |
| 1YSC | 2.8 ångströms structure of yeast serine carboxypeptidase | x-ray diffraction | A | NAG | 2 (best 0.65) |
| P00729 | AlphaFold monomer V2.0 prediction for carboxypeptidase Y (P00729) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1WPX chain A against the predicted model P00729: TM-score 0.99, RMSD 0.66 Å
- 1WPX chain A against the predicted model P00729: TM-score 0.99, RMSD 0.66 Å
- 1CPY chain A against the predicted model P00729: TM-score 0.98, RMSD 1.07 Å
- 1CPY chain A against the predicted model P00729: TM-score 0.98, RMSD 1.07 Å
- 1YSC chain A against the predicted model P00729: TM-score 0.98, RMSD 1.09 Å
- 1YSC chain A against the predicted model P00729: TM-score 0.98, RMSD 1.09 Å
Elsewhere
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