UniProt P00503
Aspartate aminotransferase, cytoplasmic (P00503)
Aspartate aminotransferase, cytoplasmic (UniProt P00503), EC 2.6.1.1, 2.6.1.3: 12 experimental structures and 1 predicted model on GenesisL1, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P00503
- Protein
- Aspartate aminotransferase, cytoplasmic
- EC
- 2.6.1.1, 2.6.1.3
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 11 · 1 record with a druggable one
Structures
13 records of P00503 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AJR | Refinement and comparison of the crystal structures of pig cytosolic aspartate aminotransferase and… | x-ray diffraction | A, B | — | — |
| 1AJR | Refinement and comparison of the crystal structures of pig cytosolic aspartate aminotransferase and… | x-ray diffraction | A, B | — | — |
| 1AJS | Refinement and comparison of the crystal structures of pig cytosolic aspartate aminotransferase and… | x-ray diffraction | A, B | — | — |
| 1AJS | Refinement and comparison of the crystal structures of pig cytosolic aspartate aminotransferase and… | x-ray diffraction | A, B | — | — |
| 5TON | Crystal structure of aat H143L mutant | x-ray diffraction | A, B | — | — |
| 5TOQ | High resolution crystal structure of aat | x-ray diffraction | A, B | — | — |
| 5TOR | Crystal structure of aat D222T mutant | x-ray diffraction | A, B | — | — |
| 5TOT | Crystal structure of aat H143L:H189L double mutant | x-ray diffraction | A, B | — | — |
| 5VJZ | Joint X-ray/neutron structure of aspartate aminotransferase with alpha-methyl-aspartate at pH 7.5 | neutron diffraction, x-ray diffraction | A, B | — | — |
| 5VJZ | Joint X-RAY/NEUTRON structure of aspartate aminotransferase with alpha-methyl-aspartate at pH 7.5 | neutron diffraction; x-ray diffraction | A, B | — | — |
| 5VK7 | aspartate aminotransferase pH 4.0 | x-ray diffraction | A, B | — | 11 (best 0.71) |
| 5VK7 | Aspartate aminotransferase pH 4.0 | x-ray diffraction | A, B | — | — |
| P00503 | AlphaFold monomer V2.0 prediction for aspartate aminotransferase, cytoplasmic (P00503) | predicted | A | — | — |
Experiment against prediction
- 1AJR chain A against the predicted model P00503: TM-score 0.99, RMSD 0.68 Å
- 1AJR chain A against the predicted model P00503: TM-score 0.99, RMSD 0.68 Å
- 5TON chain A against the predicted model P00503: TM-score 0.99, RMSD 0.69 Å
- 1AJR chain B against the predicted model P00503: TM-score 0.99, RMSD 0.70 Å
- 5TOR chain A against the predicted model P00503: TM-score 0.99, RMSD 0.71 Å
- 5TOQ chain A against the predicted model P00503: TM-score 0.99, RMSD 0.73 Å
- 5VK7 chain A against the predicted model P00503: TM-score 0.99, RMSD 0.74 Å
- 5VK7 chain A against the predicted model P00503: TM-score 0.99, RMSD 0.74 Å
- 1AJS chain B against the predicted model P00503: TM-score 0.99, RMSD 0.75 Å
- 1AJS chain B against the predicted model P00503: TM-score 0.99, RMSD 0.75 Å
Elsewhere
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