UniProt P00484
Chloramphenicol acetyltransferase 3 (P00484)
Chloramphenicol acetyltransferase 3 (UniProt P00484), EC 2.3.1.28: 14 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P00484
- Protein
- Chloramphenicol acetyltransferase 3
- EC
- 2.3.1.28
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 7 · 1 record with a druggable one
Structures
15 records of P00484 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1CIA | Replacement of catalytic histidine-195 of chloramphenicol acetyltransferase: evidence for a general… | x-ray diffraction | A | — | — |
| 1CIA | Replacement of catalytic histidine-195 of chloramphenicol acetyltransferase: evidence for a general… | x-ray diffraction | A | — | — |
| 1CLA | Evidence for transition-state stabilization by serine-148 in the catalytic mechanism of… | x-ray diffraction | A | — | — |
| 1CLA | Evidence for transition-state stabilization by serine-148 in the catalytic mechanism of… | x-ray diffraction | A | — | — |
| 1QCA | Quadruple mutant Q92C, N146F, Y168F, I172V type III cat complexed with fusidic acid. crystals grown… | x-ray diffraction | A | — | — |
| 1QCA | Quadruple mutant Q92C, N146F, Y168F, I172V type III cat complexed with fusidic acid. crystals grown… | x-ray diffraction | A | — | — |
| 2CLA | Crystal structure of the asp-199-asn mutant of chloramphenicol acetyltransferase to 2.35 ångströms… | x-ray diffraction | A | — | — |
| 2CLA | Crystal structure of the asp-199-asn mutant of chloramphenicol acetyltransferase to 2.35 ångströms… | x-ray diffraction | A | — | — |
| 3CLA | Refined crystal structure of type III chloramphenicol acetyltransferase at 1.75 ångströms resolution | x-ray diffraction | A | — | — |
| 3CLA | Refined crystal structure of type III chloramphenicol acetyltransferase at 1.75 ångströms resolution | x-ray diffraction | A | — | — |
| 4CLA | Alternative binding modes for chloramphenicol and 1-substituted chloramphenicol analogues revealed… | x-ray diffraction | A | — | — |
| 4CLA | Alternative binding modes for chloramphenicol and 1-substituted chloramphenicol analogues revealed… | x-ray diffraction | A | — | — |
| 6X7Q | Chloramphenicol acetyltransferase type III in complex with chloramphenicol and… | x-ray diffraction | A, B, C | UTA, ZN, CLM | 7 (best 0.79) |
| 6X7Q | Chloramphenicol acetyltransferase type III in complex with chloramphenicol and… | x-ray diffraction | A, B, C | UTA, ZN, CLM | — |
| P00484 | AlphaFold monomer V2.0 prediction for chloramphenicol acetyltransferase 3 (P00484) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2CLA chain A against the predicted model P00484: TM-score 0.99, RMSD 0.53 Å
- 2CLA chain A against the predicted model P00484: TM-score 0.99, RMSD 0.53 Å
- 4CLA chain A against the predicted model P00484: TM-score 0.99, RMSD 0.55 Å
- 4CLA chain A against the predicted model P00484: TM-score 0.99, RMSD 0.55 Å
- 1CIA chain A against the predicted model P00484: TM-score 0.99, RMSD 0.56 Å
- 1CIA chain A against the predicted model P00484: TM-score 0.99, RMSD 0.56 Å
- 3CLA chain A against the predicted model P00484: TM-score 0.99, RMSD 0.56 Å
- 3CLA chain A against the predicted model P00484: TM-score 0.99, RMSD 0.56 Å
- 1CLA chain A against the predicted model P00484: TM-score 0.99, RMSD 0.57 Å
- 1CLA chain A against the predicted model P00484: TM-score 0.99, RMSD 0.57 Å
Elsewhere
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