UniProt P00445
Copper-zinc superoxide dismutase (P00445)
Copper-zinc superoxide dismutase (UniProt P00445), EC 1.15.1.1: 24 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P00445
- Protein
- Copper-zinc superoxide dismutase
- EC
- 1.15.1.1
- Experimental structures
- 24
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 13 · 2 records with a druggable one
Structures
25 records of P00445 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1B4L | 15 atmosphere oxygen yeast CU/ZN superoxide dismutase room temperature (298K) structure | x-ray diffraction | A | CU, ZN | — |
| 1B4L | 15 atmosphere oxygen yeast CU/ZN superoxide dismutase room temperature (298K) structure | x-ray diffraction | A | — | — |
| 1B4T | H48C yeast CU(II)/ZN superoxide dismutase room temperature (298K) structure | x-ray diffraction | A | CU, ZN, CL | — |
| 1B4T | H48C yeast CU(II)/ZN superoxide dismutase room temperature (298K) structure | x-ray diffraction | A | — | — |
| 1F18 | Crystal structure of yeast copper-zinc superoxide dismutase mutant GLY85ARG | x-ray diffraction | A | CU, ZN | — |
| 1F18 | Crystal structure of yeast copper-zinc superoxide dismutase mutant GLY85ARG | x-ray diffraction | A | — | — |
| 1F1A | Crystal structure of yeast H48Q cuznsod fals mutant analog | x-ray diffraction | A | CU, ZN | — |
| 1F1A | Crystal structure of yeast H48Q cuznsod fals mutant analog | x-ray diffraction | A | — | — |
| 1F1D | Crystal structure of yeast H46C cuznsod mutant | x-ray diffraction | A | CU, ZN | — |
| 1F1D | Crystal structure of yeast H46C cuznsod mutant | x-ray diffraction | A | — | — |
| 1F1G | Crystal structure of yeast cuznsod exposed to nitric oxide | x-ray diffraction | A, B, C, D, E, F | CU, ZN, PO4 | 7 (best 0.76) |
| 1F1G | Crystal structure of yeast cuznsod exposed to nitric oxide | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1JCV | Reduced bridge-broken yeast CU/ZN superoxide dismutase low temperature (-180C) structure | x-ray diffraction | A | CU, ZN | — |
| 1JCV | Reduced bridge-broken yeast CU/ZN superoxide dismutase low temperature (-180C) structure | x-ray diffraction | A | — | — |
| 1JK9 | Heterodimer between H48F-ySOD1 and yCCS | x-ray diffraction | A, C | ZN, SO4 | 6 (best 0.78) |
| 1JK9 | Heterodimer between H48F-YSOD1 and yccs | x-ray diffraction | A, C | — | — |
| 1SDY | Structure solution and molecular dynamics refinement of the yeast CU,ZN enzyme superoxide dismutase | x-ray diffraction | A, B, C, D | — | — |
| 1SDY | Structure solution and molecular dynamics refinement of the yeast cu, zn enzyme superoxide dismutase | x-ray diffraction | A, B, C, D | — | — |
| 1YAZ | Azide-bound yeast CU(II)/ZN superoxide dismutase room temperature (298K) structure | x-ray diffraction | A | — | — |
| 1YAZ | Azide-bound yeast CU(II)/ZN superoxide dismutase room temperature (298K) structure | x-ray diffraction | A | — | — |
| 1YSO | Yeast cu, zn superoxide dismutase with the reduced bridge broken | x-ray diffraction | A | — | — |
| 1YSO | Yeast cu, zn superoxide dismutase with the reduced bridge broken | x-ray diffraction | A | — | — |
| 2JCW | Reduced bridge-broken yeast CU/ZN superoxide dismutase room temperature (298K) structure | x-ray diffraction | A | — | — |
| 2JCW | Reduced bridge-broken yeast CU/ZN superoxide dismutase room temperature (298K) structure | x-ray diffraction | A | — | — |
| P00445 | AlphaFold monomer V2.0 prediction for superoxide dismutase [cu-zn] (P00445) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1B4T chain A against the predicted model P00445: TM-score 0.99, RMSD 0.34 Å
- 1B4T chain A against the predicted model P00445: TM-score 0.99, RMSD 0.34 Å
- 1B4L chain A against the predicted model P00445: TM-score 0.99, RMSD 0.35 Å
- 1B4L chain A against the predicted model P00445: TM-score 0.99, RMSD 0.35 Å
- 2JCW chain A against the predicted model P00445: TM-score 0.99, RMSD 0.35 Å
- 2JCW chain A against the predicted model P00445: TM-score 0.99, RMSD 0.35 Å
- 1YSO chain A against the predicted model P00445: TM-score 0.99, RMSD 0.35 Å
- 1YSO chain A against the predicted model P00445: TM-score 0.99, RMSD 0.35 Å
- 1F1A chain A against the predicted model P00445: TM-score 0.99, RMSD 0.36 Å
- 1F1A chain A against the predicted model P00445: TM-score 0.99, RMSD 0.36 Å
Elsewhere
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