UniProt P00367
Glutamate dehydrogenase 1, mitochondrial (P00367)
Glutamate dehydrogenase 1, mitochondrial (UniProt P00367), EC 1.4.1.3: 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 60 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P00367
- Protein
- Glutamate dehydrogenase 1, mitochondrial
- EC
- 1.4.1.3
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 60 · 3 records with a druggable one
Structures
9 records of P00367 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1L1F | Structure of human glutamate dehydrogenase-apo form | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1L1F | Structure of human glutamate dehydrogenase-apo form | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1NR1 | Crystal structure of the R463A mutant of human Glutamate dehydrogenase | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1NR1 | Crystal structure of the R463A mutant of human glutamate dehydrogenase | x-ray diffraction | A, B, C, D, E, F | — | — |
| 6DQG | Human glutamate dehydrogenase, H454Y mutant | x-ray diffraction | A, B, C, D, E, F | PO4 | 20 (best 0.91) |
| 6DQG | Human glutamate dehydrogenase, H454Y mutant | x-ray diffraction | A, B, C, D, E, F | PO4 | — |
| 7UZM | Glutamate dehydrogenase 1 from human liver | electron microscopy | A, B, C, D, E, F | — | 20 (best 0.87) |
| 8KGY | Human glutamate dehydrogenase I | electron microscopy | A, B, C, D, E, F | — | 20 (best 0.90) |
| P00367 | AlphaFold monomer V2.0 prediction for glutamate dehydrogenase 1, mitochondrial (P00367) | predicted | A | — | — |
Ligands
- PO4 · Phosphate ion · in 2 records
Experiment against prediction
- 1NR1 chain B against the predicted model P00367: TM-score 0.92, RMSD 2.47 Å
- 1NR1 chain B against the predicted model P00367: TM-score 0.92, RMSD 2.47 Å
- 1NR1 chain D against the predicted model P00367: TM-score 0.92, RMSD 2.51 Å
- 1NR1 chain D against the predicted model P00367: TM-score 0.92, RMSD 2.51 Å
- 1L1F chain B against the predicted model P00367: TM-score 0.91, RMSD 2.63 Å
- 1L1F chain B against the predicted model P00367: TM-score 0.91, RMSD 2.63 Å
- 8KGY chain B against the predicted model P00367: TM-score 0.91, RMSD 2.51 Å
- 8KGY chain D against the predicted model P00367: TM-score 0.91, RMSD 2.52 Å
- 8KGY chain A against the predicted model P00367: TM-score 0.91, RMSD 2.51 Å
- 1NR1 chain E against the predicted model P00367: TM-score 0.91, RMSD 2.68 Å
Elsewhere
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