UniProt P00355
Glyceraldehyde-3-phosphate dehydrogenase (P00355)
Glyceraldehyde-3-phosphate dehydrogenase (UniProt P00355), EC 1.2.1.12, 2.6.99.-: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 12 pockets. Binding sites, druggability and experiment against…
- UniProt
- P00355
- Protein
- Glyceraldehyde-3-phosphate dehydrogenase
- EC
- 1.2.1.12, 2.6.99.-
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 12 · 2 records with a druggable one
Structures
5 records of P00355 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5DDI | Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from pig muscle - holo enzyme - at… | x-ray diffraction | P, R, S | SO4, NAD | 8 (best 0.76) |
| 5DDI | Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from pig muscle - holo enzyme - at… | x-ray diffraction | P, R, S | — | — |
| 5TSO | Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from pig muscle complexed with… | x-ray diffraction | P, R, S | SO4, NAD, PHN | 4 (best 0.77) |
| 5TSO | Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from pig muscle complexed with… | x-ray diffraction | P, R, S | SO4, NAD, PHN | — |
| P00355 | AlphaFold monomer V2.0 prediction for glyceraldehyde-3-phosphate dehydrogenase (P00355) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5TSO chain P against the predicted model P00355: TM-score 1.00, RMSD 0.29 Å
- 5TSO chain P against the predicted model P00355: TM-score 1.00, RMSD 0.29 Å
- 5TSO chain R against the predicted model P00355: TM-score 1.00, RMSD 0.30 Å
- 5TSO chain R against the predicted model P00355: TM-score 1.00, RMSD 0.30 Å
- 5TSO chain S against the predicted model P00355: TM-score 1.00, RMSD 0.32 Å
- 5TSO chain S against the predicted model P00355: TM-score 1.00, RMSD 0.32 Å
- 5DDI chain P against the predicted model P00355: TM-score 0.98, RMSD 0.90 Å
- 5DDI chain P against the predicted model P00355: TM-score 0.98, RMSD 0.90 Å
- 5DDI chain S against the predicted model P00355: TM-score 0.98, RMSD 0.91 Å
- 5DDI chain S against the predicted model P00355: TM-score 0.98, RMSD 0.91 Å
Elsewhere
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