UniProt P00343
L-lactate dehydrogenase (P00343)
L-lactate dehydrogenase (UniProt P00343), EC 1.1.1.27: 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00343
- Protein
- L-lactate dehydrogenase
- EC
- 1.1.1.27
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
9 records of P00343 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1LLC | Structure determination of the allosteric L-lactate dehydrogenase from lactobacillus casei at 3.0… | x-ray diffraction | A | — | — |
| 1LLC | Structure determination of the allosteric L-lactate dehydrogenase from lactobacillus casei at 3.0… | x-ray diffraction | A | — | — |
| 2ZQY | T-state structure of allosteric L-lactate dehydrogenase from Lactobacillus casei | x-ray diffraction | A, B, C, D | — | — |
| 2ZQY | T-state structure of allosteric L-lactate dehydrogenase from lactobacillus casei | x-ray diffraction | A, B, C, D | — | — |
| 2ZQZ | R-state structure of allosteric L-lactate dehydrogenase from Lactobacillus casei | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2ZQZ | R-state structure of allosteric L-lactate dehydrogenase from lactobacillus casei | x-ray diffraction | A, B, C, D, E, F | — | — |
| 6JML | Re-refined structure of R-state L-lactate dehydrogenase fromLactobacillus casei | x-ray diffraction | A, B, C, D, E, F | SO4 | 20 (best 0.84) |
| 6JML | Re-refined structure of R-state L-lactate dehydrogenase fromlactobacillus casei | x-ray diffraction | A, B, C, D, E, F | SO4 | — |
| P00343 | AlphaFold monomer V2.0 prediction for L-lactate dehydrogenase (P00343) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 6JML chain C against the predicted model P00343: TM-score 1.00, RMSD 0.36 Å
- 6JML chain C against the predicted model P00343: TM-score 1.00, RMSD 0.36 Å
- 6JML chain F against the predicted model P00343: TM-score 1.00, RMSD 0.41 Å
- 6JML chain A against the predicted model P00343: TM-score 1.00, RMSD 0.41 Å
- 6JML chain A against the predicted model P00343: TM-score 1.00, RMSD 0.41 Å
- 6JML chain D against the predicted model P00343: TM-score 1.00, RMSD 0.44 Å
- 6JML chain D against the predicted model P00343: TM-score 1.00, RMSD 0.44 Å
- 2ZQZ chain A against the predicted model P00343: TM-score 1.00, RMSD 0.44 Å
- 2ZQZ chain A against the predicted model P00343: TM-score 1.00, RMSD 0.44 Å
- 6JML chain B against the predicted model P00343: TM-score 1.00, RMSD 0.45 Å
Elsewhere
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