UniProt P00341
M4 apo-lactate dehydrogenase (P00341)
M4 apo-lactate dehydrogenase (UniProt P00341), EC 1.1.1.27: 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P00341
- Protein
- M4 apo-lactate dehydrogenase
- EC
- 1.1.1.27
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 3 · 1 record with a druggable one
Structures
9 records of P00341 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1LDM | Refined crystal structure of dogfish M4 apo-lactate dehydrogenase | x-ray diffraction | A | — | — |
| 1LDM | Refined crystal structure of dogfish M4 apo-lactate dehydrogenase | x-ray diffraction | A | — | — |
| 3LDH | A comparison of the structures of apo dogfish m4 lactate dehydrogenase and its ternary complexes | x-ray diffraction | A | — | — |
| 3LDH | A comparison of the structures of apo dogfish M4 lactate dehydrogenase and its ternary complexes | x-ray diffraction | A | — | — |
| 6LDH | Refined crystal structure of dogfish M4 apo-lactate dehydrogenase | x-ray diffraction | A | SO4 | — |
| 6LDH | Refined crystal structure of dogfish M4 apo-lactate dehydrogenase | x-ray diffraction | A | ACE, SO4 | — |
| 8LDH | Refined crystal structure of dogfish M4 apo-lactate dehydrogenase | x-ray diffraction | A | — | 3 (best 0.67) |
| 8LDH | Refined crystal structure of dogfish M4 apo-lactate dehydrogenase | x-ray diffraction | A | ACE | — |
| P00341 | AlphaFold monomer V2.0 prediction for L-lactate dehydrogenase a chain (P00341) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8LDH chain A against the predicted model P00341: TM-score 0.99, RMSD 0.78 Å
- 8LDH chain A against the predicted model P00341: TM-score 0.99, RMSD 0.78 Å
- 6LDH chain A against the predicted model P00341: TM-score 0.99, RMSD 0.79 Å
- 6LDH chain A against the predicted model P00341: TM-score 0.99, RMSD 0.79 Å
- 1LDM chain A against the predicted model P00341: TM-score 0.98, RMSD 1.37 Å
- 1LDM chain A against the predicted model P00341: TM-score 0.98, RMSD 1.37 Å
- 3LDH chain A against the predicted model P00341: TM-score 0.95, RMSD 1.68 Å
- 3LDH chain A against the predicted model P00341: TM-score 0.95, RMSD 1.68 Å
Elsewhere
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