UniProt P00330
Alcohol dehydrogenase 1 (P00330)
Alcohol dehydrogenase 1 (UniProt P00330), EC 1.1.1.1: 5 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 25 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00330
- Protein
- Alcohol dehydrogenase 1
- EC
- 1.1.1.1
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 25 · 2 records with a druggable one
Structures
6 records of P00330 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4W6Z | Yeast alcohol dehydrogenase I, saccharomyces cerevisiae fermentative enzyme | x-ray diffraction | A, B, C, D | — | — |
| 4W6Z | Yeast alcohol dehydrogenase I, saccharomyces cerevisiae fermentative enzyme | x-ray diffraction | A, B, C, D | — | — |
| 5ENV | Yeast alcohol dehydrogenase with bound coenzyme | x-ray diffraction | A, B | ZN, NAD | 5 (best 0.77) |
| 5ENV | Yeast alcohol dehydrogenase with bound coenzyme | x-ray diffraction | A, B | — | — |
| 7NTM | Cryo-EM structure of S.cerevisiae native alcohol dehydrogenase 1 (ADH1) in its tetrameric apo state | electron microscopy | A, B, D, C | ZN | 20 (best 0.75) |
| P00330 | AlphaFold monomer V2.0 prediction for alcohol dehydrogenase 1 (P00330) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4W6Z chain B against the predicted model P00330: TM-score 0.99, RMSD 0.80 Å
- 4W6Z chain B against the predicted model P00330: TM-score 0.99, RMSD 0.80 Å
- 5ENV chain B against the predicted model P00330: TM-score 0.99, RMSD 0.83 Å
- 5ENV chain B against the predicted model P00330: TM-score 0.99, RMSD 0.83 Å
- 7NTM chain A against the predicted model P00330: TM-score 0.98, RMSD 0.88 Å
- 7NTM chain D against the predicted model P00330: TM-score 0.98, RMSD 0.89 Å
- 7NTM chain C against the predicted model P00330: TM-score 0.98, RMSD 0.89 Å
- 7NTM chain B against the predicted model P00330: TM-score 0.98, RMSD 0.89 Å
- 4W6Z chain D against the predicted model P00330: TM-score 0.98, RMSD 0.91 Å
- 4W6Z chain D against the predicted model P00330: TM-score 0.98, RMSD 0.91 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.