UniProt O96019
Actin-like protein 6A (O96019)
Actin-like protein 6A (UniProt O96019): 15 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 52 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O96019
- Protein
- Actin-like protein 6A
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 52 · 13 records with a druggable one
Structures
16 records of O96019 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6LTJ | Structure of nucleosome-bound human BAF complex | electron microscopy | J | — | 4 (best 0.86) |
| 6LTJ | Structure of nucleosome-bound human baf complex | electron microscopy | J | — | — |
| 7VDV | The overall structure of human chromatin remodeling PBAF-nucleosome complex | electron microscopy | N | — | 3 (best 0.82) |
| 7VDV | The overall structure of human chromatin remodeling pbaf-nucleosome complex | electron microscopy | N | — | — |
| 7Y8R | The nucleosome-bound human PBAF complex | electron microscopy | K | — | 3 (best 0.90) |
| 8QR1 | Cryo-EM structure of the human Tip60 complex | electron microscopy | K | — | 3 (best 0.88) |
| 8X15 | Structure of nucleosome-bound SRCAP-C in the apo state | electron microscopy | T | ATP | 2 (best 0.87) |
| 8X19 | Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state | electron microscopy | T | ATP | 2 (best 0.85) |
| 8X1C | Structure of nucleosome-bound SRCAP-C in the ADP-bound state | electron microscopy | T | ATP | 2 (best 0.87) |
| 8XVG | Structure of human NuA4/TIP60 complex | electron microscopy | I, J | ADP | 3 (best 0.86) |
| 8XVT | The core subcomplex of human NuA4/TIP60 complex | electron microscopy | I, J | ADP | 5 (best 0.84) |
| 9C4B | Second BAF53a of the human TIP60 complex | electron microscopy | A | — | 3 (best 0.81) |
| 9C57 | Reconstituted P400 Subcomplex of the human TIP60 complex | electron microscopy | M, L | ATP | 5 (best 0.85) |
| 9C62 | P400 subcomplex of the native human TIP60 complex | electron microscopy | L, M | — | 6 (best 0.88) |
| 9C6N | ARP module of the human TIP60 complex | electron microscopy | L | ATP | 11 (best 0.88) |
| O96019 | AlphaFold monomer V2.0 prediction for actin-like protein 6A (O96019) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8X19 chain T against the predicted model O96019: TM-score 0.99, RMSD 0.72 Å
- 8X1C chain T against the predicted model O96019: TM-score 0.99, RMSD 0.81 Å
- 8X15 chain T against the predicted model O96019: TM-score 0.99, RMSD 0.88 Å
- 9C6N chain L against the predicted model O96019: TM-score 0.98, RMSD 1.00 Å
- 8QR1 chain K against the predicted model O96019: TM-score 0.98, RMSD 1.02 Å
- 9C4B chain A against the predicted model O96019: TM-score 0.98, RMSD 1.13 Å
- 9C57 chain L against the predicted model O96019: TM-score 0.98, RMSD 1.14 Å
- 6LTJ chain J against the predicted model O96019: TM-score 0.97, RMSD 1.24 Å
- 6LTJ chain J against the predicted model O96019: TM-score 0.97, RMSD 1.24 Å
- 7VDV chain N against the predicted model O96019: TM-score 0.97, RMSD 1.27 Å
Elsewhere
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