UniProt O95863
Zinc finger protein SNAI1 (O95863)
Zinc finger protein SNAI1 (UniProt O95863): 10 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O95863
- Protein
- Zinc finger protein SNAI1
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 7 · 4 records with a druggable one
Structures
11 records of O95863 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2Y48 | Crystal structure of LSD1-CoREST in complex with a N-terminal SNAIL peptide | x-ray diffraction | C | — | — |
| 2Y48 | Crystal structure of LSD1-corest in complex with a N- terminal snail peptide | x-ray diffraction | C | — | — |
| 3W5K | Crystal structure of Snail1 and importin beta complex | x-ray diffraction | B | — | — |
| 3W5K | Crystal structure of SNAIL1 and importin beta complex | x-ray diffraction | B | — | — |
| 4QLI | A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3… | x-ray diffraction | B | — | — |
| 4QLI | A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3… | x-ray diffraction | B | — | — |
| 8BOX | LSD1-CoREST in complex with AW4 and SNAG peptide | x-ray diffraction | C | SV9 | 2 (best 0.86) |
| 8F59 | LSD1-CoREST in complex with AW2 and SNAG peptide | x-ray diffraction | C | XB6 | 2 (best 0.87) |
| 8FDV | LSD1-CoREST in complex N-formyl FAD and SNAG peptide | x-ray diffraction | C | HUF | 1 (best 0.85) |
| 8FJ7 | LSD1-CoREST in complex with T108 and SNAG peptide | x-ray diffraction | C | Y0Z | 2 (best 0.87) |
| O95863 | AlphaFold monomer V2.0 prediction for zinc finger protein SNAI1 (O95863) | predicted | A | — | — |
Ligands
- HUF · [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4S)-5-[5-methanoyl-7,8-dimethyl-2,4-bis(oxidanylidene)-1H-benzo[g]pteridin-10-yl]-2,3,4-tris(oxidanyl)pentyl] hydrogen phosphate · in 1 record
- SV9 · [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S})-5-[7,8-dimethyl-2,4-bis(oxidanylidene)-5-[3-[4-(3-phenylphenyl)phenyl]propanoyl]-1~{H}-benzo[g]pteridin-10-yl]-2,3,4-tris(oxidanyl)pentyl] hydrogen phosphate · in 1 record
- XB6 · [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-{5-[3-([1,1'-biphenyl]-4-yl)propanoyl]-7,8-dimethyl-2,4-dioxo-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl}-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) · in 1 record
- Y0Z · [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-[7,8-dimethyl-2,4-dioxo-5-{3-[3-(phenylcarbamoyl)phenyl]propanoyl}-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate · in 1 record
Experiment against prediction
- 8F59 chain C against the predicted model O95863: TM-score 0.92, RMSD 0.15 Å
- 8FJ7 chain C against the predicted model O95863: TM-score 0.92, RMSD 0.15 Å
- 8BOX chain C against the predicted model O95863: TM-score 0.73, RMSD 0.34 Å
- 4QLI chain B against the predicted model O95863: TM-score 0.55, RMSD 0.43 Å
- 4QLI chain B against the predicted model O95863: TM-score 0.55, RMSD 0.43 Å
- 2Y48 chain C against the predicted model O95863: TM-score 0.41, RMSD 1.10 Å
- 2Y48 chain C against the predicted model O95863: TM-score 0.41, RMSD 1.10 Å
- 8FDV chain C against the predicted model O95863: TM-score 0.38, RMSD 1.59 Å
- 3W5K chain B against the predicted model O95863: TM-score 0.38, RMSD 4.28 Å
- 3W5K chain B against the predicted model O95863: TM-score 0.38, RMSD 4.28 Å
Elsewhere
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