UniProt O95461
Xylosyl- and glucuronyltransferase LARGE1 (O95461)
Xylosyl- and glucuronyltransferase LARGE1 (UniProt O95461), EC 2.4.-.-, 2.4.1.-: 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 49 pockets. Binding sites, druggability and experiment against…
- UniProt
- O95461
- Protein
- Xylosyl- and glucuronyltransferase LARGE1
- EC
- 2.4.-.-, 2.4.1.-, 2.4.2.-
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 49 · 3 records with a druggable one
Structures
4 records of O95461 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7UI6 | CryoEM structure of LARGE1 from C1 reconstruction | electron microscopy | A, B | MN | 19 (best 0.84) |
| 7UI7 | CryoEM structure of LARGE1 from C2 reconstruction | electron microscopy | A, B | MN | 15 (best 0.86) |
| 7ZVJ | Homodimeric structure of LARGE1 | x-ray diffraction | A, B | NAG, PO4, MN | 15 (best 0.84) |
| O95461 | AlphaFold monomer V2.0 prediction for large xylosyl- and glucuronyltransferase 1 (O95461) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7UI6 chain A against the predicted model O95461: TM-score 0.99, RMSD 0.92 Å
- 7UI7 chain A against the predicted model O95461: TM-score 0.99, RMSD 0.94 Å
- 7UI6 chain B against the predicted model O95461: TM-score 0.99, RMSD 0.96 Å
- 7UI7 chain B against the predicted model O95461: TM-score 0.99, RMSD 1.01 Å
- 7ZVJ chain B against the predicted model O95461: TM-score 0.99, RMSD 1.04 Å
- 7ZVJ chain A against the predicted model O95461: TM-score 0.98, RMSD 1.23 Å
Elsewhere
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