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UniProt O95340

Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (O95340)

Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (UniProt O95340), EC 2.7.1.25, 2.7.7.4: 7 experimental structures on GenesisL1, 5 ligands bound, 15 pockets. Binding sites, pockets, druggability and 3D structures in…

UniProt
O95340
Protein
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2
EC
2.7.1.25, 2.7.7.4
Experimental structures
7
Predicted models
0
Ligands
5
Pockets
15 · 2 records with a druggable one

Structures

7 records of O95340 in the MolNFT archive: 7 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
2AX4Crystal structure of the kinase domain of human 3'-phosphoadenosine 5'-phosphosulphate synthetase 2x-ray diffractionA, B, C, D——
2AX4Crystal structure of the kinase domain of human 3'- phosphoadenosine 5'-phosphosulphate synthetase 2x-ray diffractionA, B, C, D——
7FH3Crystal structure of the ATP sulfurylase domain of human PAPSS2x-ray diffractionA, BSO4, BGC10 (best 0.74)
7FH3Crystal structure of the ATP sulfurylase domain of human PAPSS2x-ray diffractionA, BSO4, BGC—
7FHACrystal structure of the ATP sulfurylase domain of human PAPSS2 in complex with apsx-ray diffractionA, BADX, BGC, K, SO4—
8I1OCrystal structure of APSK2 domain from human PAPSS2 in complex with exogenous APS and ADPx-ray diffractionA, B, C, DADP, ADX5 (best 0.84)
O95340AlphaFold monomer V2.0 prediction for bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2…———

Ligands

  • BGC · beta-D-glucopyranose · in 3 records
  • SO4 · Sulfate ion · in 3 records
  • ADX · Adenosine-5'-phosphosulfate · in 2 records
  • ADP · Adenosine-5'-diphosphate · in 1 record
  • K · Potassium ion · in 1 record

Elsewhere

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