UniProt O95169
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (O95169)
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (UniProt O95169): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 13 pockets. Binding sites, druggability and experiment…
- UniProt
- O95169
- Protein
- NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 13 · 4 records with a druggable one
Structures
7 records of O95169 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5XTC | Cryo-EM structure of human respiratory complex I transmembrane arm | electron microscopy | c | PEE, CDL | 5 (best 0.86) |
| 5XTC | Cryo-EM structure of human respiratory complex I transmembrane arm | electron microscopy | c | PEE, CDL | — |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | c | PEE, CDL | 2 (best 0.85) |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | c | PEE, CDL | — |
| 5XTH | Cryo-EM structure of human respiratory supercomplex I1III2IV1 | electron microscopy | c | PEE, CDL | 2 (best 0.86) |
| 5XTI | Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 | electron microscopy | c, Bc | PEE, CDL | 2 (best 0.86) |
| O95169 | AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8… | predicted | A | — | 2 (best 0.37) |
Ligands
Experiment against prediction
- 5XTC chain c against the predicted model O95169: TM-score 0.94, RMSD 1.20 Å
- 5XTC chain c against the predicted model O95169: TM-score 0.94, RMSD 1.20 Å
- 5XTD chain c against the predicted model O95169: TM-score 0.94, RMSD 1.20 Å
- 5XTD chain c against the predicted model O95169: TM-score 0.94, RMSD 1.20 Å
- 5XTI chain Bc against the predicted model O95169: TM-score 0.94, RMSD 1.20 Å
- 5XTI chain c against the predicted model O95169: TM-score 0.94, RMSD 1.20 Å
- 5XTH chain c against the predicted model O95169: TM-score 0.94, RMSD 1.20 Å
Elsewhere
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