UniProt O94966
Ubiquitin carboxyl-terminal hydrolase 19 (O94966)
Ubiquitin carboxyl-terminal hydrolase 19 (UniProt O94966), EC 3.4.19.12: 10 experimental structures and 1 predicted model on GenesisL1, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O94966
- Protein
- Ubiquitin carboxyl-terminal hydrolase 19
- EC
- 3.4.19.12
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 18 · 3 records with a druggable one
Structures
11 records of O94966 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1WH0 | Solution structure of the CS domain of human USP19 | solution nmr | A | — | — |
| 1WH0 | Solution structure of the cs domain of human USP19 | solution nmr | A | — | — |
| 4X3G | Crystal structure of SIAH1 SINA domain in complex with a USP19 peptide | x-ray diffraction | C, D | — | — |
| 4X3G | Crystal structure of SIAH1 sina domain in complex with a USP19 peptide | x-ray diffraction | C, D | — | — |
| 6K7W | Solution Structure of the CS1 Domain of USP19 | solution nmr | A | — | 1 (best 0.68) |
| 6K7W | Solution structure of the CS1 domain of USP19 | — | — | — | |
| 6KHV | Solution Structure of the CS2 Domain of USP19 | solution nmr | A | — | 1 (best 0.70) |
| 6KHV | Solution structure of the CS2 domain of USP19 | solution nmr | A | — | — |
| 6KQV | Solution Structure of the UbL Domain of USP19 | solution nmr | A | — | — |
| 6KQV | Solution structure of the ubl domain of USP19 | solution nmr | A | — | — |
| O94966 | AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 19 (O94966) | predicted | A | — | 16 (best 0.74) |
Experiment against prediction
- 1WH0 chain A against the predicted model O94966: TM-score 0.79, RMSD 2.28 Å
- 1WH0 chain A against the predicted model O94966: TM-score 0.79, RMSD 2.28 Å
- 6KHV chain A against the predicted model O94966: TM-score 0.70, RMSD 3.09 Å
- 6KHV chain A against the predicted model O94966: TM-score 0.70, RMSD 3.09 Å
- 6KQV chain A against the predicted model O94966: TM-score 0.61, RMSD 3.43 Å
- 6KQV chain A against the predicted model O94966: TM-score 0.61, RMSD 3.43 Å
- 6K7W chain A against the predicted model O94966: TM-score 0.60, RMSD 3.53 Å
- 4X3G chain D against the predicted model O94966: TM-score 0.54, RMSD 1.03 Å
- 4X3G chain D against the predicted model O94966: TM-score 0.54, RMSD 1.03 Å
- 4X3G chain C against the predicted model O94966: TM-score 0.51, RMSD 1.51 Å
Elsewhere
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