UniProt O94646
Mediator complex subunit 8 (O94646)
Mediator complex subunit 8 (UniProt O94646): 10 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O94646
- Protein
- Mediator complex subunit 8
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
11 records of O94646 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3C0T | Structure of the Schizosaccharomyces pombe Mediator subcomplex Med8C/18 | x-ray diffraction | B | — | — |
| 3C0T | Structure of the schizosaccharomyces pombe mediator subcomplex MED8C/18 | x-ray diffraction | B | — | — |
| 4H63 | Structure of the Schizosaccharomyces pombe Mediator head module | x-ray diffraction | H | — | — |
| 4H63 | Structure of the schizosaccharomyces pombe mediator head module | x-ray diffraction | H | — | — |
| 5N9J | Core Mediator of transcriptional regulation | x-ray diffraction | U | — | — |
| 5N9J | Core mediator of transcriptional regulation | x-ray diffraction | U | — | — |
| 5U0P | Cryo-EM structure of the transcriptional Mediator | electron microscopy | H | — | 5 (best 0.77) |
| 5U0P | Cryo-EM structure of the transcriptional mediator | electron microscopy | H | — | — |
| 5U0S | Cryo-EM structure of the Mediator-RNAPII complex | electron microscopy | H | — | — |
| 5U0S | Cryo-EM structure of the mediator-rnapii complex | electron microscopy | H | — | — |
| O94646 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 8 (O94646) | predicted | A | — | — |
Experiment against prediction
- 4H63 chain H against the predicted model O94646: TM-score 0.68, RMSD 2.89 Å
- 4H63 chain H against the predicted model O94646: TM-score 0.68, RMSD 2.89 Å
- 5U0P chain H against the predicted model O94646: TM-score 0.66, RMSD 3.17 Å
- 5U0P chain H against the predicted model O94646: TM-score 0.66, RMSD 3.17 Å
- 5N9J chain U against the predicted model O94646: TM-score 0.65, RMSD 3.65 Å
- 5N9J chain U against the predicted model O94646: TM-score 0.65, RMSD 3.65 Å
- 5U0S chain H against the predicted model O94646: TM-score 0.65, RMSD 3.43 Å
- 5U0S chain H against the predicted model O94646: TM-score 0.65, RMSD 3.43 Å
- 3C0T chain B against the predicted model O94646: TM-score 0.61, RMSD 1.74 Å
- 3C0T chain B against the predicted model O94646: TM-score 0.61, RMSD 1.74 Å
Elsewhere
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