UniProt O94376
Mediator of RNA polymerase II transcription subunit 21 (O94376)
Mediator of RNA polymerase II transcription subunit 21 (UniProt O94376): 6 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O94376
- Protein
- Mediator of RNA polymerase II transcription subunit 21
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
7 records of O94376 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5N9J | Core Mediator of transcriptional regulation | x-ray diffraction | D | — | — |
| 5N9J | Core mediator of transcriptional regulation | x-ray diffraction | D | — | — |
| 5U0P | Cryo-EM structure of the transcriptional Mediator | electron microscopy | U | — | 2 (best 0.80) |
| 5U0P | Cryo-EM structure of the transcriptional mediator | electron microscopy | U | — | — |
| 5U0S | Cryo-EM structure of the Mediator-RNAPII complex | electron microscopy | U | — | — |
| 5U0S | Cryo-EM structure of the mediator-rnapii complex | electron microscopy | U | — | — |
| O94376 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 21… | predicted | A | — | — |
Experiment against prediction
- 5U0P chain U against the predicted model O94376: TM-score 0.54, RMSD 4.14 Å
- 5U0P chain U against the predicted model O94376: TM-score 0.54, RMSD 4.14 Å
- 5N9J chain D against the predicted model O94376: TM-score 0.52, RMSD 2.33 Å
- 5N9J chain D against the predicted model O94376: TM-score 0.52, RMSD 2.33 Å
- 5U0S chain U against the predicted model O94376: TM-score 0.49, RMSD 4.16 Å
- 5U0S chain U against the predicted model O94376: TM-score 0.49, RMSD 4.16 Å
Elsewhere
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