GL1X · GenesisL1 explorer

UniProt O92972

NS5B (O92972)

NS5B (UniProt O92972): 105 experimental structures on GenesisL1, 2 ligands bound, 13 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
O92972
Protein
NS5B
Experimental structures
105
Predicted models
0
Ligands
2
Pockets
13 · 1 record with a druggable one

Structures

105 records of O92972 in the MolNFT archive: 105 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
2MTSThree-Dimensional Structure and Interaction Studies of Hepatitis C Virus p7 in…solution nmrA——
2MTSThree-dimensional structure and interaction studies of hepatitis C virus P7 in…solution nmrA——
2XHUHCV-J4 NS5B Polymerase Orthorhombic Crystal Formx-ray diffractionA, B——
2XHUHCV-J4 NS5B polymerase orthorhombic crystal formx-ray diffractionA, B——
2XHVHCV-J4 NS5B Polymerase Point Mutant Orthorhombic Crystal Formx-ray diffractionA, B——
2XHVHCV-J4 NS5B polymerase point mutant orthorhombic crystal formx-ray diffractionA, B——
2XHWHCV-J4 NS5B Polymerase Trigonal Crystal Formx-ray diffractionA——
2XHWHCV-J4 NS5B polymerase trigonal crystal formx-ray diffractionA——
2YOJHCV NS5B polymerase complexed with pyridonylindole compoundx-ray diffractionA, B——
2YOJHCV NS5B polymerase complexed with pyridonylindole compoundx-ray diffractionA, B——
3CSOHCV Polymerase in complex with a 1,5 Benzodiazepine inhibitorx-ray diffractionA, B——
3CSOHCV polymerase in complex with a 1,5 benzodiazepine inhibitorx-ray diffractionA, B——
3GNVHCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 1bx-ray diffractionA, B——
3GNVHCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 1Bx-ray diffractionA, B——
3GNWHCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 4cx-ray diffractionA, B——
3GNWHCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 4Cx-ray diffractionA, B——
3GOLHCV NS5b polymerase in complex with 1,5 benzodiazepine inhibitor (R)-11dx-ray diffractionA, B——
3GOLHCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor (R)- 11Dx-ray diffractionA, B——
3HKYHCV NS5B polymerase genotype 1b in complex with 1,5 benzodiazepine 6x-ray diffractionA, B——
3HKYHCV NS5B polymerase genotype 1B in complex with 1,5 benzodiazepine 6x-ray diffractionA, B——
3LKHInhibitors of Hepatitis C Virus Polymerase: Synthesis and Characterization of Novel…x-ray diffractionA, B——
3LKHInhibitors of hepatitis C virus polymerase: synthesis and characterization of novel…x-ray diffractionA, B——
3MWVCrystal structure of HCV NS5B polymerasex-ray diffractionA, B——
3MWVCrystal structure of HCV NS5B polymerasex-ray diffractionA, B——
3MWWCrystal structure of HCV NS5B polymerasex-ray diffractionA, B——
3MWWCrystal structure of HCV NS5B polymerasex-ray diffractionA, B——
3SKAI. Novel HCV NS5B Polymerase Inhibitors: Discovery of Indole 2- Carboxylic Acids with…x-ray diffractionA, B——
3SKAI. novel HCV NS5B polymerase inhibitors: discovery of indole 2- carboxylic acids with…x-ray diffractionA, B——
3SKEI. Novel HCV NS5B Polymerase Inhibitors: Discovery of Indole 2- Carboxylic Acids with…x-ray diffractionA, B——
3SKEI. novel HCV NS5B polymerase inhibitors: discovery of indole 2- carboxylic acids with…x-ray diffractionA, B——
3SKHI. Novel HCV NS5B Polymerase Inhibitors: Discovery of Indole 2- Carboxylic Acids with…x-ray diffractionA, B——
3SKHI. novel HCV NS5B polymerase inhibitors: discovery of indole 2- carboxylic acids with…x-ray diffractionA, B——
3TYQSAR development and discovery of potent indole-based inhibitors of the hepatitis c virus NS5B…x-ray diffractionA, B——
3TYQSar development and discovery of potent indole-based inhibitors of the hepatitis C virus NS5B…x-ray diffractionA, B——
3TYVSAR development and discovery of potent indole-based inhibitors of the hepatitis C virus NS5B…x-ray diffractionA, B——
3TYVSar development and discovery of potent indole-based inhibitors of the hepatitis C virus NS5B…x-ray diffractionA, B——
3U4ONovel HCV NS5B polymerase Inhibitors: Discovery of Indole C2 Acyl sulfonamidesx-ray diffractionA, B——
3U4ONovel HCV NS5B polymerase inhibitors: discovery of indole C2 acyl sulfonamidesx-ray diffractionA, B——
3U4RNovel HCV NS5B polymerase Inhibitors: Discovery of Indole C2 Acyl sulfonamidesx-ray diffractionA, B——
3U4RNovel HCV NS5B polymerase inhibitors: discovery of indole C2 acyl sulfonamidesx-ray diffractionA, B——
3UPHSynthesis of novel 4,5-dihydrofurano indoles and their evaluation as HCV NS5B polymerase inhibitorsx-ray diffractionA, B——
3UPHSynthesis of novel 4,5-dihydrofurano indoles and their evaluation as HCV NS5B polymerase inhibitorsx-ray diffractionA, B——
3UPISynthesis of novel 4,5-dihydrofurano indoles and their evaluation as HCV NS5B polymerase inhibitorsx-ray diffractionA, B——
3UPISynthesis of novel 4,5-dihydrofurano indoles and their evaluation as HCV NS5B polymerase inhibitorsx-ray diffractionA, B——
4DRUHCV NS5B in complex with macrocyclic INDOLE INHIBITORx-ray diffractionA, B——
4DRUHCV NS5B in complex with macrocyclic indole inhibitorx-ray diffractionA, B——
4EAWHCV NS5B in complex with IDX375x-ray diffractionA, B——
4EAWHCV NS5B in complex with IDX375x-ray diffractionA, B——
4GMCCrystal structure of HCV NS5B polymerase in complex with a thumb inhibitorx-ray diffractionA, B——
4GMCCrystal structure of HCV NS5B polymerase in complex with a thumb inhibitorx-ray diffractionA, B——
4IZ0Crystal structure of HCV NS5B polymerase in complex with…x-ray diffractionA, B——
4IZ0Crystal structure of HCV NS5B polymerase in complex with 2,4,5…x-ray diffractionA, B——
4J02Crystal structure of hcv ns5b polymerase in complex with…x-ray diffractionA, B——
4J02Crystal structure of HCV NS5B polymerase in complex with [(1R)-5,8…x-ray diffractionA, B——
4J04Crystal structure of hcv ns5b polymerase in complex with…x-ray diffractionA, B——
4J04Crystal structure of HCV NS5B polymerase in complex with 4-chloro-2…x-ray diffractionA, B——
4J06Crystal structure of hcv ns5b polymerase in complex with…x-ray diffractionA, B——
4J06Crystal structure of HCV NS5B polymerase in complex with 2-{[(5…x-ray diffractionA, B——
4J08Crystal structure of hcv ns5b polymerase in complex with…x-ray diffractionA, B——
4J08Crystal structure of HCV NS5B polymerase in complex with 2-{[(4…x-ray diffractionA, B——

45 records more on the page itself.

Ligands

  • 55W · 1-[4-(7-amino-5-methylpyrazolo[1,5-a]pyrimidin-2-yl)phenyl]-3-{[(R)-(2,4-dimethylphenyl)(methoxy)phosphoryl]amino}-1H-pyrazole-4-carboxylic acid · in 1 record
  • SO4 · Sulfate ion · in 1 record

Elsewhere

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