UniProt O91936
Non-structural protein 4A,Serine protease NS3 (O91936)
Non-structural protein 4A,Serine protease NS3 (UniProt O91936), EC 3.4.21.98, 3.6.1.15: 2 experimental structures on GenesisL1, 3 ligands bound, 2 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O91936
- Protein
- Non-structural protein 4A,Serine protease NS3
- EC
- 3.4.21.98, 3.6.1.15, 3.6.4.13
- Experimental structures
- 2
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 2 · 0 records with a druggable one
Structures
2 records of O91936 in the MolNFT archive: 2 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6P6V | HCV NS3/4A protease domain of genotype 5a in complex with glecaprevir | x-ray diffraction | A | ZN, CL, O31 | 2 (best 0.33) |
| 6P6V | HCV NS3/4A protease domain of genotype 5A in complex with glecaprevir | x-ray diffraction | A | ZN, CL, O31 | — |
Ligands
- CL · Chloride ion · in 2 records
- O31 · (3ar,7s,10s,12r,21e,24ar)-7-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl) sulfonyl]carbamoyl}cyclopropyl]-20,20-difluoro-5,8-dioxo-2,3,3A,5,6,7,8,11,12,20,23,24A-dodecahydro-1H, 10H-9,12-methanocyclopenta[18,19][1,10,17,3, 6]trioxadiazacyclononadecino[11,12-b]quinoxaline-10-carboxamide · in 2 records
- ZN · Zinc ion · in 2 records
Elsewhere
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