UniProt O88846
E3 ubiquitin-protein ligase RNF4 (O88846)
E3 ubiquitin-protein ligase RNF4 (UniProt O88846): 8 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O88846
- Protein
- E3 ubiquitin-protein ligase RNF4
- Experimental structures
- 8
- Predicted models
- 1
Structures
9 records of O88846 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3NG2 | Crystal structure of the RNF4 ring domain dimer | x-ray diffraction | A, B | — | — |
| 3NG2 | Crystal structure of the RNF4 ring domain dimer | x-ray diffraction | A, B | — | — |
| 4AP4 | Rnf4 - ubch5a - ubiquitin heterotrimeric complex | x-ray diffraction | A | — | — |
| 4AP4 | RNF4 - UBCH5A - ubiquitin heterotrimeric complex | x-ray diffraction | A | — | — |
| 5AIT | A complex of of RNF4-RING domain, UbeV2, Ubc13-Ub (isopeptide crosslink) | x-ray diffraction | A | — | — |
| 5AIT | A complex of of RNF4-ring domain, UBEV2, UBC13-ub (isopeptide crosslink) | x-ray diffraction | A | — | — |
| 5AIU | A complex of RNF4-RING domain, Ubc13-Ub (isopeptide crosslink) | x-ray diffraction | A | — | — |
| 5AIU | A complex of RNF4-ring domain, UBC13-ub (isopeptide crosslink) | x-ray diffraction | A | — | — |
| O88846 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase RNF4 (O88846) | predicted | A | — | — |
Experiment against prediction
- 3NG2 chain B against the predicted model O88846: TM-score 0.81, RMSD 1.44 Å
- 3NG2 chain B against the predicted model O88846: TM-score 0.81, RMSD 1.44 Å
- 3NG2 chain A against the predicted model O88846: TM-score 0.80, RMSD 1.40 Å
- 3NG2 chain A against the predicted model O88846: TM-score 0.80, RMSD 1.40 Å
- 5AIU chain A against the predicted model O88846: TM-score 0.49, RMSD 0.75 Å
- 5AIU chain A against the predicted model O88846: TM-score 0.49, RMSD 0.75 Å
- 4AP4 chain A against the predicted model O88846: TM-score 0.49, RMSD 1.93 Å
- 4AP4 chain A against the predicted model O88846: TM-score 0.49, RMSD 1.93 Å
- 5AIT chain A against the predicted model O88846: TM-score 0.49, RMSD 1.92 Å
- 5AIT chain A against the predicted model O88846: TM-score 0.49, RMSD 1.92 Å
Elsewhere
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