UniProt O86311
Multidrug efflux system ATP-binding protein Rv1218c (O86311)
Multidrug efflux system ATP-binding protein Rv1218c (UniProt O86311), EC 7.6.2.-: 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 23 pockets. Binding sites, druggability and experiment against…
- UniProt
- O86311
- Protein
- Multidrug efflux system ATP-binding protein Rv1218c
- EC
- 7.6.2.-
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 23 · 3 records with a druggable one
Structures
4 records of O86311 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8K1M | mycobacterial efflux pump, apo state | electron microscopy | C, D | — | 8 (best 0.76) |
| 8K1N | mycobacterial efflux pump, substrate-bound state | electron microscopy | E, D | — | 6 (best 0.77) |
| 8K1O | mycobacterial efflux pump, AMPPNP bound state | electron microscopy | B, C | CDL, ANP, MG | 7 (best 0.83) |
| O86311 | AlphaFold monomer V2.0 prediction for multidrug efflux system ATP- binding protein RV1218C (O86311) | predicted | A | — | 2 (best 0.44) |
Ligands
Experiment against prediction
- 8K1O chain B against the predicted model O86311: TM-score 0.98, RMSD 0.89 Å
- 8K1O chain C against the predicted model O86311: TM-score 0.97, RMSD 0.99 Å
- 8K1N chain E against the predicted model O86311: TM-score 0.97, RMSD 0.89 Å
- 8K1M chain C against the predicted model O86311: TM-score 0.97, RMSD 0.92 Å
Elsewhere
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