UniProt O81098
DNA-directed RNA polymerases II and IV subunit 5A (O81098)
DNA-directed RNA polymerases II and IV subunit 5A (UniProt O81098): 7 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O81098
- Protein
- DNA-directed RNA polymerases II and IV subunit 5A
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 6 · 4 records with a druggable one
Structures
8 records of O81098 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7EU0 | The cryo-EM structure of A. thaliana Pol IV-RDR2 backtracked complex | electron microscopy | E | — | 1 (best 0.74) |
| 7EU0 | The cryo-EM structure of a. thaliana pol IV-RDR2 backtracked complex | electron microscopy | E | — | — |
| 7EU1 | The cryo-EM structure of a. thaliana pol IV-RDR2 holoenzyme | electron microscopy | E | — | — |
| 8XMB | NTP-bound Pol IV transcription elongation complex | electron microscopy | E | — | — |
| 8XMC | Post-translocated Pol IV transcription elongation complex | electron microscopy | E | — | 1 (best 0.72) |
| 8XMD | Pre-translocated Pol IV transcription elongation complex | electron microscopy | E | — | 1 (best 0.65) |
| 8XME | Backtracked Pol IV transcription elongation complex | electron microscopy | E | — | 1 (best 0.72) |
| O81098 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases II and IV subunit 5A (O81098) | predicted | A | — | 2 (best 0.45) |
Experiment against prediction
- 8XMC chain E against the predicted model O81098: TM-score 0.97, RMSD 0.98 Å
- 8XMB chain E against the predicted model O81098: TM-score 0.96, RMSD 1.03 Å
- 8XMD chain E against the predicted model O81098: TM-score 0.96, RMSD 1.03 Å
- 8XME chain E against the predicted model O81098: TM-score 0.96, RMSD 1.04 Å
- 7EU0 chain E against the predicted model O81098: TM-score 0.96, RMSD 1.08 Å
- 7EU0 chain E against the predicted model O81098: TM-score 0.96, RMSD 1.08 Å
- 7EU1 chain E against the predicted model O81098: TM-score 0.94, RMSD 1.50 Å
Elsewhere
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