UniProt O77448
Telomerase reverse transcriptase (O77448)
Telomerase reverse transcriptase (UniProt O77448), EC 2.7.7.49: 17 experimental structures on GenesisL1, 75 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O77448
- Protein
- Telomerase reverse transcriptase
- EC
- 2.7.7.49
- Experimental structures
- 17
- Predicted models
- 0
- Pockets
- 75 · 5 records with a druggable one
Structures
17 records of O77448 in the MolNFT archive: 17 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2B2A | Crystal Structure of the TEN domain of the Telomerase Reverse Transcriptase | x-ray diffraction | A, B, C | — | — |
| 2B2A | Crystal structure of the ten domain of the telomerase reverse transcriptase | x-ray diffraction | A, B, C | — | — |
| 2R4G | The high resolution structure of the RNA-binding domain of telomerase | x-ray diffraction | A | — | — |
| 2R4G | The high resolution structure of the RNA-binding domain of telomerase | x-ray diffraction | A | — | — |
| 5C9H | Structural Basis of Template Boundary Definition in Tetrahymena Telomerase | x-ray diffraction | A, B | — | 12 (best 0.51) |
| 5C9H | Structural basis of template boundary definition in tetrahymena telomerase | x-ray diffraction | A, B | — | — |
| 6D6V | CryoEM structure of Tetrahymena telomerase with telomeric DNA at 4.8 Angstrom resolution | electron microscopy | A | — | 18 (best 0.88) |
| 6D6V | Cryoem structure of tetrahymena telomerase with telomeric DNA at 4.8 ångström resolution | electron microscopy | A | — | — |
| 7LMA | Tetrahymena telomerase T3D2 structure at 3.3 Angstrom | electron microscopy | A | — | — |
| 7LMA | Tetrahymena telomerase T3D2 structure at 3.3 ångström | electron microscopy | A | — | — |
| 7LMB | Tetrahymena telomerase T5D5 structure at 3.8 ångström | electron microscopy | A | — | — |
| 7UY5 | Tetrahymena telomerase with CST | electron microscopy | A | — | 14 (best 0.80) |
| 7UY5 | Tetrahymena telomerase with cst | electron microscopy | A | — | — |
| 7UY6 | Tetrahymena telomerase at 2.9 Angstrom resolution | electron microscopy | A | — | 17 (best 0.81) |
| 7UY6 | Tetrahymena telomerase at 2.9 ångström resolution | electron microscopy | A | — | — |
| 8GAP | Structure of LARP7 protein p65-telomerase RNA complex in telomerase | electron microscopy | A | — | 14 (best 0.83) |
| O77448 | AlphaFold monomer V2.0 prediction for telomerase reverse transcriptase (O77448) | — | — | — |
Elsewhere
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