UniProt O75821
Eukaryotic translation initiation factor 3 subunit G (O75821)
Eukaryotic translation initiation factor 3 subunit G (UniProt O75821): 17 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75821
- Protein
- Eukaryotic translation initiation factor 3 subunit G
- Experimental structures
- 17
- Predicted models
- 1
Structures
18 records of O75821 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2CQ0 | solution structure of RNA binding domain in eukaryotic translation initiation factor 3 subunit 4 | solution nmr | A | — | — |
| 2CQ0 | Solution structure of RNA binding domain in eukaryotic translation initiation factor 3 subunit 4 | solution nmr | A | — | — |
| 2MJC | Zn-binding domain of eukaryotic translation initiation factor 3, subunit G | solution nmr | A | — | — |
| 2MJC | Zn-binding domain of eukaryotic translation initiation factor 3, subunit G | solution nmr | A | — | — |
| 5K0Y | m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2… | electron microscopy | M, O | — | — |
| 5K0Y | M48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying EIF2… | electron microscopy | M, O | — | — |
| 6YBS | Structure of a human 48S translational initiation complex - head | electron microscopy | o | — | — |
| 7QP6 | Structure of the human 48S initiation complex in open state (h48S AUG open) | electron microscopy | o | — | — |
| 7QP7 | Structure of the human 48S initiation complex in closed state (h48S AUG closed) | electron microscopy | o | — | — |
| 8OZ0 | Structure of a human 48S translation initiation complex with eIF4F and eIF4A | electron microscopy | 7 | — | — |
| 8PJ1 | Structure of human 48S translation initiation complex in open codon scanning state (48S-1) | electron microscopy | o | — | — |
| 8PJ2 | Structure of human 48S translation initiation complex in AUG recognition state after eIF5-induced… | electron microscopy | o | — | — |
| 8PJ5 | Structure of human 48S translation initiation complex after eIF2 release prior 60S subunit joining… | electron microscopy | o | — | — |
| 8PJ6 | Structure of human 48S translation initiation complex with initiator tRNA, eIF1A and eIF3… | electron microscopy | o | — | — |
| 8PPL | MERS-CoV Nsp1 bound to the human 43S pre-initiation complex | electron microscopy | Io | — | — |
| 8XXM | Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G | electron microscopy | 3G | — | — |
| 8XXN | Cryo-EM structure of the human 43S ribosome with PDCD4 | electron microscopy | 3G | — | — |
| O75821 | AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 3 subunit G (O75821) | predicted | A | — | — |
Experiment against prediction
- 8XXN chain 3G against the predicted model O75821: TM-score 0.98, RMSD 0.50 Å
- 8XXM chain 3G against the predicted model O75821: TM-score 0.97, RMSD 0.62 Å
- 8PPL chain Io against the predicted model O75821: TM-score 0.95, RMSD 0.75 Å
- 7QP6 chain o against the predicted model O75821: TM-score 0.94, RMSD 0.83 Å
- 7QP7 chain o against the predicted model O75821: TM-score 0.94, RMSD 0.86 Å
- 6YBS chain o against the predicted model O75821: TM-score 0.93, RMSD 0.90 Å
- 8PJ6 chain o against the predicted model O75821: TM-score 0.92, RMSD 1.05 Å
- 5K0Y chain O against the predicted model O75821: TM-score 0.92, RMSD 1.13 Å
- 5K0Y chain O against the predicted model O75821: TM-score 0.92, RMSD 1.13 Å
- 8PJ5 chain o against the predicted model O75821: TM-score 0.91, RMSD 1.04 Å
Elsewhere
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