UniProt O75794
Cell division cycle protein 123 homolog (O75794)
Cell division cycle protein 123 homolog (UniProt O75794): 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75794
- Protein
- Cell division cycle protein 123 homolog
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 22 · 2 records with a druggable one
Structures
3 records of O75794 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8PHD | Structure of Human Cdc123 bound to domain 3 of eIF2 gamma and ATP | x-ray diffraction | A, C | ATP, MG | 12 (best 0.76) |
| 8PHV | Structure of Human selenomethionylated Cdc123 bound to domain 3 of eIF2 gamma | x-ray diffraction | A, C | ATP | 10 (best 0.77) |
| O75794 | AlphaFold monomer V2.0 prediction for cell division cycle protein 123 homolog (O75794) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8PHV chain A against the predicted model O75794: TM-score 0.91, RMSD 2.38 Å
- 8PHD chain A against the predicted model O75794: TM-score 0.91, RMSD 2.34 Å
- 8PHD chain C against the predicted model O75794: TM-score 0.91, RMSD 2.39 Å
- 8PHV chain C against the predicted model O75794: TM-score 0.90, RMSD 2.71 Å
Elsewhere
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