UniProt O75751
Solute carrier family 22 member 3 (O75751)
Solute carrier family 22 member 3 (UniProt O75751): 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75751
- Protein
- Solute carrier family 22 member 3
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 15 · 4 records with a druggable one
Structures
4 records of O75751 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7ZH0 | Structure of human OCT3 in lipid nanodisc | electron microscopy | A | — | 4 (best 0.79) |
| 7ZH6 | Structure of human OCT3 in complex with inhibitor Corticosterone | electron microscopy | A | C0R | 5 (best 0.81) |
| 7ZHA | Structure of human OCT3 in complex with inhibitor decynium-22 | electron microscopy | A | JDW | 3 (best 0.82) |
| O75751 | AlphaFold monomer V2.0 prediction for solute carrier family 22 member 3 (O75751) | predicted | A | — | 3 (best 0.80) |
Ligands
Experiment against prediction
- 7ZHA chain A against the predicted model O75751: TM-score 0.87, RMSD 3.42 Å
- 7ZH6 chain A against the predicted model O75751: TM-score 0.87, RMSD 3.31 Å
- 7ZH0 chain A against the predicted model O75751: TM-score 0.86, RMSD 3.51 Å
Elsewhere
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