UniProt O75570
Peptide chain release factor 1, mitochondrial (O75570)
Peptide chain release factor 1, mitochondrial (UniProt O75570): 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- O75570
- Protein
- Peptide chain release factor 1, mitochondrial
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 7 · 5 records with a druggable one
Structures
7 records of O75570 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8OIN | 55S mammalian mitochondrial ribosome with mtRF1 and P-site tRNA | electron microscopy | Aa | MG, FME | — |
| 8OIP | 28S mammalian mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA | electron microscopy | Aa | MG | 1 (best 0.84) |
| 8OIQ | 39S mammalian mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA | electron microscopy | Aa | MG, FME | — |
| 8OIR | 55S human mitochondrial ribosome with mtRF1 and P-site tRNA | electron microscopy | Aa | MG, MET | 2 (best 0.86) |
| 8OIS | 28S human mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA | electron microscopy | Aa | MG, MET | 1 (best 0.86) |
| 8OIT | 39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA | electron microscopy | Aa | MG, MET | 1 (best 0.85) |
| O75570 | AlphaFold monomer V2.0 prediction for peptide chain release factor 1, mitochondrial (O75570) | predicted | A | — | 2 (best 0.82) |
Ligands
Experiment against prediction
- 8OIP chain Aa against the predicted model O75570: TM-score 0.86, RMSD 3.01 Å
- 8OIQ chain Aa against the predicted model O75570: TM-score 0.86, RMSD 3.01 Å
- 8OIN chain Aa against the predicted model O75570: TM-score 0.86, RMSD 3.02 Å
- 8OIR chain Aa against the predicted model O75570: TM-score 0.82, RMSD 3.33 Å
- 8OIT chain Aa against the predicted model O75570: TM-score 0.82, RMSD 3.34 Å
- 8OIS chain Aa against the predicted model O75570: TM-score 0.82, RMSD 3.36 Å
Elsewhere
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