UniProt O75489
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (O75489)
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (UniProt O75489), EC 1.6.5.3, 1.6.99.3: 6 experimental structures and 1 predicted model on GenesisL1, 20 pockets. Binding sites, druggability and experiment…
- UniProt
- O75489
- Protein
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
- EC
- 1.6.5.3, 1.6.99.3
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 20 · 4 records with a druggable one
Structures
7 records of O75489 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5XTB | Cryo-EM structure of human respiratory complex I matrix arm | electron microscopy | P | — | 6 (best 0.89) |
| 5XTB | Cryo-EM structure of human respiratory complex I matrix arm | electron microscopy | P | — | — |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | P | — | 7 (best 0.86) |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | P | — | — |
| 5XTH | Cryo-EM structure of human respiratory supercomplex I1III2IV1 | electron microscopy | P | — | 4 (best 0.89) |
| 5XTI | Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 | electron microscopy | P, BP | — | 3 (best 0.89) |
| O75489 | AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 3… | predicted | A | — | — |
Experiment against prediction
- 5XTI chain P against the predicted model O75489: TM-score 0.98, RMSD 0.79 Å
- 5XTI chain BP against the predicted model O75489: TM-score 0.98, RMSD 0.79 Å
- 5XTD chain P against the predicted model O75489: TM-score 0.98, RMSD 0.79 Å
- 5XTD chain P against the predicted model O75489: TM-score 0.98, RMSD 0.79 Å
- 5XTH chain P against the predicted model O75489: TM-score 0.98, RMSD 0.79 Å
- 5XTB chain P against the predicted model O75489: TM-score 0.98, RMSD 0.79 Å
- 5XTB chain P against the predicted model O75489: TM-score 0.98, RMSD 0.79 Å
Elsewhere
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