UniProt O75486
Transcription initiation protein SPT3 homolog (O75486)
Transcription initiation protein SPT3 homolog (UniProt O75486): 4 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75486
- Protein
- Transcription initiation protein SPT3 homolog
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 14 · 4 records with a druggable one
Structures
5 records of O75486 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7KTR | Cryo-EM structure of the human SAGA coactivator complex (TRRAP, core) | electron microscopy | I | — | 5 (best 0.88) |
| 7KTR | Cryo-EM structure of the human saga coactivator complex (trrap, core) | electron microscopy | I | — | — |
| 7KTS | Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module) | electron microscopy | I | — | 3 (best 0.88) |
| 8H7G | Cryo-EM structure of the human SAGA complex | electron microscopy | E | — | 2 (best 0.91) |
| O75486 | AlphaFold monomer V2.0 prediction for transcription initiation protein SPT3 homolog (O75486) | predicted | A | — | 4 (best 0.66) |
Experiment against prediction
- 8H7G chain E against the predicted model O75486: TM-score 0.86, RMSD 2.31 Å
- 7KTS chain I against the predicted model O75486: TM-score 0.79, RMSD 2.52 Å
- 7KTR chain I against the predicted model O75486: TM-score 0.79, RMSD 2.52 Å
- 7KTR chain I against the predicted model O75486: TM-score 0.79, RMSD 2.52 Å
Elsewhere
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