UniProt O75419
Cell division control protein 45 homolog (O75419)
Cell division control protein 45 homolog (UniProt O75419): 5 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75419
- Protein
- Cell division control protein 45 homolog
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 7 · 2 records with a druggable one
Structures
6 records of O75419 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5DGO | Crystal structure of cell division cycle protein 45 (CDC45) | x-ray diffraction | A | — | — |
| 6XTX | CryoEM structure of human CMG bound to ATPgammaS and DNA | electron microscopy | E | — | 3 (best 0.87) |
| 6XTX | Cryoem structure of human cmg bound to atpgammas and DNA | electron microscopy | E | — | — |
| 6XTY | Cryoem structure of human cmg bound to and-1 (cmga) | electron microscopy | E | — | — |
| 7PLO | H. sapiens replisome-CUL2/LRR1 complex | electron microscopy | C | — | 4 (best 0.90) |
| O75419 | AlphaFold monomer V2.0 prediction for cell division control protein 45 homolog (O75419) | predicted | A | — | — |
Experiment against prediction
- 5DGO chain A against the predicted model O75419: TM-score 1.00, RMSD 0.56 Å
- 7PLO chain C against the predicted model O75419: TM-score 0.98, RMSD 1.23 Å
- 6XTX chain E against the predicted model O75419: TM-score 0.97, RMSD 1.51 Å
- 6XTX chain E against the predicted model O75419: TM-score 0.97, RMSD 1.51 Å
- 6XTY chain E against the predicted model O75419: TM-score 0.97, RMSD 1.51 Å
Elsewhere
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