UniProt O75367
Vacuolar transporter chaperone 4,Core histone macro-H2A.1 (O75367)
Vacuolar transporter chaperone 4,Core histone macro-H2A.1 (UniProt O75367): 16 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 32 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- O75367
- Protein
- Vacuolar transporter chaperone 4,Core histone macro-H2A.1
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 32 · 2 records with a druggable one
Structures
17 records of O75367 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1U35 | Crystal structure of the nucleosome core particle containing the histone domain of macroH2A | x-ray diffraction | C, G | — | — |
| 1U35 | Crystal structure of the nucleosome core particle containing the histone domain of MACROH2A | x-ray diffraction | C, G | — | — |
| 1ZR5 | Crystal structure of the macro-domain of human core histone variant macroH2A1.2 | x-ray diffraction | A, B | — | — |
| 1ZR5 | Crystal structure of the macro-domain of human core histone variant MACROH2A1.2 | x-ray diffraction | A, B | — | — |
| 2F8N | 2.9 Angstrom X-ray structure of hybrid macroH2A nucleosomes | x-ray diffraction | G | — | — |
| 2F8N | 2.9 ångström X-ray structure of hybrid MACROH2A nucleosomes | x-ray diffraction | G | — | — |
| 3HSV | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin… | x-ray diffraction | M | — | — |
| 3HSV | Structures of spop-substrate complexes: insights into molecular architectures of btb-CUL3 ubiquitin… | x-ray diffraction | M | — | — |
| 3IID | Crystal structure of the macro domain of human histone MACROH2A1.1 in complex with ADP-ribose (form… | x-ray diffraction | — | — | |
| 3IIF | Crystal structure of the macro domain of human histone MACROH2A1.1 in complex with ADP-ribose (form… | x-ray diffraction | — | — | |
| 3IVB | Structures of SPOP-Substrate Complexes: Insights into Architectures of BTB-Cul3 Ubiquitin Ligases… | x-ray diffraction | M | — | — |
| 3IVB | Structures of spop-substrate complexes: insights into architectures of btb-CUL3 ubiquitin ligases… | x-ray diffraction | M | — | — |
| 5IIT | Structure of SPX domain of the yeast inorganic polyphophate polymerase Vtc4 crystallized by… | x-ray diffraction | A, B, C, D | SO4, MG | 20 (best 0.77) |
| 5IIT | Structure of spx domain of the yeast inorganic polyphophate polymerase VTC4 crystallized by… | x-ray diffraction | A, B, C, D | — | — |
| 5LNC | Structure of SPX domain of the yeast inorganic polyphophate polymerase Vtc4 crystallized by… | x-ray diffraction | A, B | — | 12 (best 0.78) |
| 5LNC | Structure of spx domain of the yeast inorganic polyphophate polymerase VTC4 crystallized by… | x-ray diffraction | A, B | — | — |
| O75367 | AlphaFold monomer V2.0 prediction for core histone macro-H2A.1 (O75367) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1ZR5 chain B against the predicted model O75367: TM-score 0.99, RMSD 0.59 Å
- 1ZR5 chain B against the predicted model O75367: TM-score 0.99, RMSD 0.59 Å
- 1ZR5 chain A against the predicted model O75367: TM-score 0.98, RMSD 0.86 Å
- 1ZR5 chain A against the predicted model O75367: TM-score 0.98, RMSD 0.86 Å
- 1U35 chain C against the predicted model O75367: TM-score 0.94, RMSD 1.15 Å
- 1U35 chain C against the predicted model O75367: TM-score 0.94, RMSD 1.15 Å
- 2F8N chain G against the predicted model O75367: TM-score 0.93, RMSD 1.32 Å
- 2F8N chain G against the predicted model O75367: TM-score 0.93, RMSD 1.32 Å
- 5IIT chain C against the predicted model O75367: TM-score 0.56, RMSD 2.36 Å
- 5IIT chain C against the predicted model O75367: TM-score 0.56, RMSD 2.36 Å
Elsewhere
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