UniProt O75175
CCR4-NOT transcription complex subunit 3 (O75175)
CCR4-NOT transcription complex subunit 3 (UniProt O75175): 10 experimental structures and 1 predicted model on GenesisL1, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75175
- Protein
- CCR4-NOT transcription complex subunit 3
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 15 · 2 records with a druggable one
Structures
11 records of O75175 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4C0D | Structure of the NOT module of the human CCR4-NOT complex (CNOT1-CNOT2-CNOT3) | x-ray diffraction | C | — | — |
| 4C0D | Structure of the not module of the human CCR4-not complex (CNOT1-CNOT2-CNOT3) | x-ray diffraction | C | — | — |
| 4C0G | Structure of the NOT-box domain of human CNOT3 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4C0G | Structure of the not-box domain of human CNOT3 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5FU6 | NOT module of the human CCR4-NOT complex (Crystallization mutant) | x-ray diffraction | C, F | — | 12 (best 0.78) |
| 5FU6 | Not module of the human CCR4-not complex (crystallization mutant) | x-ray diffraction | C, F | — | — |
| 5FU7 | drosophila nanos NBR peptide bound to the NOT module of the human CCR4-NOT complex | x-ray diffraction | C, G | — | — |
| 5FU7 | Drosophila nanos nbr peptide bound to the not module of the human CCR4-not complex | x-ray diffraction | C, G | — | — |
| 9C3H | Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site. | electron microscopy | SB | — | — |
| 9C3I | Rebuilt CNOT3/tRNA-LEU structure | electron microscopy | S | — | 3 (best 0.71) |
| O75175 | AlphaFold monomer V2.0 prediction for CCR4-not transcription complex subunit 3 (O75175) | predicted | A | — | — |
Experiment against prediction
- 4C0D chain C against the predicted model O75175: TM-score 0.99, RMSD 0.52 Å
- 4C0D chain C against the predicted model O75175: TM-score 0.99, RMSD 0.52 Å
- 4C0G chain A against the predicted model O75175: TM-score 0.99, RMSD 0.43 Å
- 4C0G chain A against the predicted model O75175: TM-score 0.99, RMSD 0.43 Å
- 4C0G chain E against the predicted model O75175: TM-score 0.98, RMSD 0.50 Å
- 4C0G chain E against the predicted model O75175: TM-score 0.98, RMSD 0.50 Å
- 4C0G chain F against the predicted model O75175: TM-score 0.97, RMSD 0.90 Å
- 4C0G chain F against the predicted model O75175: TM-score 0.97, RMSD 0.90 Å
- 5FU6 chain C against the predicted model O75175: TM-score 0.97, RMSD 0.98 Å
- 5FU6 chain C against the predicted model O75175: TM-score 0.97, RMSD 0.98 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.