UniProt O75173
O75173
O75173 (UniProt O75173): 10 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75173
- Experimental structures
- 10
- Predicted models
- 1
Structures
11 records of O75173 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2RJP | Crystal structure of ADAMTS4 with inhibitor bound | x-ray diffraction | A, B, C, D | — | — |
| 2RJP | Crystal structure of ADAMTS4 with inhibitor bound | x-ray diffraction | A, B, C, D | — | — |
| 3B2Z | Crystal Structure of ADAMTS4 (apo form) | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3B2Z | Crystal structure of ADAMTS4 (apo form) | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4WK7 | Crystal structure of human ADAMTS-4 in complex with inhibitor (compound 1… | x-ray diffraction | A | — | — |
| 4WK7 | Crystal structure of human adamts-4 in complex with inhibitor (compound 1… | x-ray diffraction | A | — | — |
| 4WKE | Crystal structure of human ADAMTS-4 in complex with inhibitor… | x-ray diffraction | A | — | — |
| 4WKE | Crystal structure of human adamts-4 in complex with inhibitor 5… | x-ray diffraction | A | — | — |
| 4WKI | Crystal structure of human ADAMTS-4 in complex with inhibitor… | x-ray diffraction | A | — | — |
| 4WKI | Crystal structure of human adamts-4 in complex with inhibitor 5… | x-ray diffraction | A | — | — |
| O75173 | AlphaFold monomer V2.0 prediction for a disintegrin and metalloproteinase with thrombospondin… | predicted | A | — | — |
Experiment against prediction
- 4WK7 chain A against the predicted model O75173: TM-score 0.99, RMSD 0.57 Å
- 4WK7 chain A against the predicted model O75173: TM-score 0.99, RMSD 0.57 Å
- 4WKE chain A against the predicted model O75173: TM-score 0.99, RMSD 0.75 Å
- 4WKE chain A against the predicted model O75173: TM-score 0.99, RMSD 0.75 Å
- 4WKI chain A against the predicted model O75173: TM-score 0.99, RMSD 0.75 Å
- 4WKI chain A against the predicted model O75173: TM-score 0.99, RMSD 0.75 Å
- 2RJP chain D against the predicted model O75173: TM-score 0.98, RMSD 0.91 Å
- 2RJP chain D against the predicted model O75173: TM-score 0.98, RMSD 0.91 Å
- 2RJP chain C against the predicted model O75173: TM-score 0.98, RMSD 0.96 Å
- 2RJP chain C against the predicted model O75173: TM-score 0.98, RMSD 0.96 Å
Elsewhere
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