UniProt O75150
E3 ubiquitin-protein ligase BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (UniProt O75150), EC 2.3.2.27: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- O75150
- Protein
- E3 ubiquitin-protein ligase BRE1B
- EC
- 2.3.2.27
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
3 records of O75150 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8GUJ | Bre1-nucleosome complex (Model II) | electron microscopy | L | ZN | — |
| 8IEJ | RNF20-RNF40/hRad6A-Ub/nucleosome complex | electron microscopy | A | ZN | 1 (best 0.68) |
| O75150 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase BRE1B (O75150) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 8IEJ chain A against the predicted model O75150: TM-score 0.94, RMSD 0.66 Å
- 8GUJ chain L against the predicted model O75150: TM-score 0.83, RMSD 1.55 Å
Elsewhere
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