UniProt O75122
CLIP-associating protein 2 (O75122)
CLIP-associating protein 2 (UniProt O75122): 9 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 30 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75122
- Protein
- CLIP-associating protein 2
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 30 · 5 records with a druggable one
Structures
10 records of O75122 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3WOY | Crystal structure of CLASP2 TOG domain (TOG2) | x-ray diffraction | A | — | — |
| 3WOY | Crystal structure of CLASP2 tog domain (TOG2) | x-ray diffraction | A | — | — |
| 5NR4 | Crystal structure of Clasp2 TOG1 domain | x-ray diffraction | A, B | — | 3 (best 0.51) |
| 5NR4 | Crystal structure of CLASP2 TOG1 domain | x-ray diffraction | A, B | — | — |
| 8WHH | Crystal structure of Se-Met derivative CLASP2 in complex with CLIP170 | x-ray diffraction | A, B, C, D | — | 14 (best 0.70) |
| 8WHI | Crystal structure of native CLASP2 in complex with CLIP170 | x-ray diffraction | A | — | 1 (best 0.54) |
| 8WHJ | Crystal structure of CLASP2 TOG4 fused with LL5beta | x-ray diffraction | A | CL | 1 (best 0.51) |
| 8WHK | Crystal structure of CLASP2 in complex with LL5beta | x-ray diffraction | A | CL | 2 (best 0.44) |
| 8WHL | Crystal structure of CLASP2 in complex with CENP-E | x-ray diffraction | B, D, C, A | — | 9 (best 0.74) |
| O75122 | AlphaFold monomer V2.0 prediction for clip-associating protein 2 (O75122) | predicted | A | — | — |
Ligands
- CL · Chloride ion · in 2 records
Experiment against prediction
- 8WHL chain B against the predicted model O75122: TM-score 0.98, RMSD 0.78 Å
- 8WHL chain A against the predicted model O75122: TM-score 0.98, RMSD 0.92 Å
- 3WOY chain A against the predicted model O75122: TM-score 0.98, RMSD 1.14 Å
- 3WOY chain A against the predicted model O75122: TM-score 0.98, RMSD 1.14 Å
- 8WHL chain D against the predicted model O75122: TM-score 0.97, RMSD 1.00 Å
- 8WHH chain D against the predicted model O75122: TM-score 0.97, RMSD 1.02 Å
- 8WHL chain C against the predicted model O75122: TM-score 0.97, RMSD 1.02 Å
- 8WHH chain B against the predicted model O75122: TM-score 0.97, RMSD 1.06 Å
- 8WHI chain A against the predicted model O75122: TM-score 0.96, RMSD 1.06 Å
- 8WHH chain C against the predicted model O75122: TM-score 0.96, RMSD 1.10 Å
Elsewhere
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