UniProt O75031
Heat shock factor 2-binding protein (O75031)
Heat shock factor 2-binding protein (UniProt O75031): 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75031
- Protein
- Heat shock factor 2-binding protein
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 18 · 2 records with a druggable one
Structures
7 records of O75031 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7BDX | Armadillo domain of HSF2BP in complex with BRCA2 peptide | x-ray diffraction | A, B, C, D | MG | 12 (best 0.84) |
| 7BDX | Armadillo domain of HSF2BP in complex with BRCA2 peptide | x-ray diffraction | A, B, C, D | MG | — |
| 7LDG | Crystal structure of the MEILB2-BRCA2 complex | x-ray diffraction | A, C | — | 6 (best 0.61) |
| 7LDG | Crystal structure of the MEILB2-BRCA2 complex | x-ray diffraction | A, C | — | — |
| 8A50 | Crystal structure of HSF2BP-ALPHA1 tetramer | x-ray diffraction | A, B | PO4 | — |
| 8A51 | Crystal structure of HSF2BP-BRME1 complex | x-ray diffraction | A | CL | — |
| O75031 | AlphaFold monomer V2.0 prediction for heat shock factor 2-binding protein (O75031) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7BDX chain C against the predicted model O75031: TM-score 0.98, RMSD 0.73 Å
- 7BDX chain C against the predicted model O75031: TM-score 0.98, RMSD 0.73 Å
- 7BDX chain D against the predicted model O75031: TM-score 0.97, RMSD 0.97 Å
- 7LDG chain C against the predicted model O75031: TM-score 0.96, RMSD 1.12 Å
- 7LDG chain C against the predicted model O75031: TM-score 0.96, RMSD 1.12 Å
- 7LDG chain A against the predicted model O75031: TM-score 0.94, RMSD 1.54 Å
- 7LDG chain A against the predicted model O75031: TM-score 0.94, RMSD 1.54 Å
- 7BDX chain B against the predicted model O75031: TM-score 0.94, RMSD 1.54 Å
- 7BDX chain B against the predicted model O75031: TM-score 0.94, RMSD 1.54 Å
- 7BDX chain A against the predicted model O75031: TM-score 0.94, RMSD 1.58 Å
Elsewhere
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