UniProt O74772
Pre-mRNA-splicing factor cwf14 (O74772)
Pre-mRNA-splicing factor cwf14 (UniProt O74772): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O74772
- Protein
- Pre-mRNA-splicing factor cwf14
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 6 · 2 records with a druggable one
Structures
5 records of O74772 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JB9 | Cryo-EM structure of the yeast spliceosome at 3.6 angstrom resolution | electron microscopy | e | — | — |
| 3JB9 | Cryo-EM structure of the yeast spliceosome at 3.6 ångström resolution | electron microscopy | e | — | — |
| 9ESH | Structure of a B-state intermediate committed to discard (Bd-I state) | electron microscopy | O | ZN | 2 (best 0.83) |
| 9ESI | Structure of a B-state intermediate committed to discard (Bd-II state) | electron microscopy | O | ZN | 4 (best 0.83) |
| O74772 | AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor CWF14 (O74772) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 9ESH chain O against the predicted model O74772: TM-score 0.95, RMSD 1.42 Å
- 9ESI chain O against the predicted model O74772: TM-score 0.94, RMSD 1.44 Å
- 3JB9 chain e against the predicted model O74772: TM-score 0.93, RMSD 1.56 Å
- 3JB9 chain e against the predicted model O74772: TM-score 0.93, RMSD 1.56 Å
Elsewhere
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