UniProt O74429
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase (O74429)
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase (UniProt O74429), EC 2.7.4.24: 5 experimental structures on GenesisL1, 8 ligands bound, 18 pockets. Binding sites, pockets, druggability and 3D structures…
- UniProt
- O74429
- Protein
- Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase
- EC
- 2.7.4.24
- Experimental structures
- 5
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 18 · 4 records with a druggable one
Structures
5 records of O74429 in the MolNFT archive: 5 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8E1H | Asp1 kinase in complex with ADP Mg 5-IP7 | x-ray diffraction | A, B | ADP, I7P, MG | 4 (best 0.81) |
| 8E1I | Asp1 kinase in complex with ATP Mg 5-IP7 | x-ray diffraction | A, B | I7P, ATP, MG | 5 (best 0.81) |
| 8E1J | Asp1 kinase in complex with 1,5-IP8 | x-ray diffraction | A, B | I8P | 5 (best 0.83) |
| 8E1S | Asp1 kinase in complex with ADPNP Mn IP6 | x-ray diffraction | A, B | ANP, IHP, MN | 4 (best 0.83) |
| O74429 | AlphaFold monomer V2.0 prediction for inositol hexakisphosphate and… | — | — | — |
Ligands
- I7P · (1R,2R,3S,4S,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy) cyclohexyl trihydrogen diphosphate · in 2 records
- MG · Magnesium ion · in 2 records
- ADP · Adenosine-5'-diphosphate · in 1 record
- ANP · Phosphoaminophosphonic acid-adenylate ester · in 1 record
- ATP · Adenosine-5'-triphosphate · in 1 record
- I8P · (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy) cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)] · in 1 record
- IHP · Inositol hexakisphosphate · in 1 record
- MN · Manganese (II) ion · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.