UniProt O70351
3-hydroxyacyl-CoA dehydrogenase type-2 (O70351)
3-hydroxyacyl-CoA dehydrogenase type-2 (UniProt O70351): 6 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O70351
- Protein
- 3-hydroxyacyl-CoA dehydrogenase type-2
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
7 records of O70351 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1E3S | Rat brain 3-hydroxyacyl-CoA dehydrogenase binary complex with NADH | x-ray diffraction | A, B, C, D | — | — |
| 1E3S | Rat brain 3-hydroxyacyl-CoA dehydrogenase binary complex with NADH | x-ray diffraction | A, B, C, D | — | — |
| 1E3W | Rat brain 3-hydroxyacyl-CoA dehydrogenase binary complex with NADH and 3-keto butyrate | x-ray diffraction | A, B, C, D | — | — |
| 1E3W | Rat brain 3-hydroxyacyl-CoA dehydrogenase binary complex with NADH and 3-keto butyrate | x-ray diffraction | A, B, C, D | — | — |
| 1E6W | Rat brain 3-hydroxyacyl-CoA dehydrogenase binary complex with NADH and estradiol | x-ray diffraction | A, B, C, D | — | — |
| 1E6W | Rat brain 3-hydroxyacyl-CoA dehydrogenase binary complex with NADH and estradiol | x-ray diffraction | A, B, C, D | — | — |
| O70351 | AlphaFold monomer V2.0 prediction for 3-hydroxyacyl-CoA dehydrogenase type-2 (O70351) | predicted | A | — | 1 (best 0.69) |
Experiment against prediction
- 1E3W chain B against the predicted model O70351: TM-score 1.00, RMSD 0.35 Å
- 1E3W chain B against the predicted model O70351: TM-score 1.00, RMSD 0.35 Å
- 1E6W chain B against the predicted model O70351: TM-score 1.00, RMSD 0.40 Å
- 1E6W chain B against the predicted model O70351: TM-score 1.00, RMSD 0.40 Å
- 1E3W chain A against the predicted model O70351: TM-score 1.00, RMSD 0.41 Å
- 1E3W chain A against the predicted model O70351: TM-score 1.00, RMSD 0.41 Å
- 1E6W chain A against the predicted model O70351: TM-score 0.99, RMSD 0.44 Å
- 1E6W chain A against the predicted model O70351: TM-score 0.99, RMSD 0.44 Å
- 1E6W chain C against the predicted model O70351: TM-score 0.99, RMSD 0.45 Å
- 1E6W chain C against the predicted model O70351: TM-score 0.99, RMSD 0.45 Å
Elsewhere
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