UniProt O70274
Protein tyrosine phosphatase type IVA 2 (O70274)
Protein tyrosine phosphatase type IVA 2 (UniProt O70274), EC 3.1.3.48: 2 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O70274
- Protein
- Protein tyrosine phosphatase type IVA 2
- EC
- 3.1.3.48
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
3 records of O70274 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5K24 | Crystal structure of the complex between phosphatase PRL-2 in the oxidized state with the Bateman… | x-ray diffraction | A, B | — | 5 (best 0.59) |
| 5K24 | Crystal structure of the complex between phosphatase prl-2 in the oxidized state with the bateman… | x-ray diffraction | A, B | — | — |
| O70274 | AlphaFold monomer V2.0 prediction for protein tyrosine phosphatase type iva 2 (O70274) | predicted | A | — | — |
Experiment against prediction
- 5K24 chain B against the predicted model O70274: TM-score 0.97, RMSD 0.87 Å
- 5K24 chain B against the predicted model O70274: TM-score 0.97, RMSD 0.87 Å
- 5K24 chain A against the predicted model O70274: TM-score 0.97, RMSD 0.91 Å
- 5K24 chain A against the predicted model O70274: TM-score 0.97, RMSD 0.91 Å
Elsewhere
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