UniProt O69762
Hydroxycinnamoyl-CoA hydratase-lyase (O69762)
Hydroxycinnamoyl-CoA hydratase-lyase (UniProt O69762): 6 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O69762
- Protein
- Hydroxycinnamoyl-CoA hydratase-lyase
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
7 records of O69762 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2J5I | Crystal Structure of Hydroxycinnamoyl-CoA Hydratase-Lyase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 2J5I | Crystal structure of hydroxycinnamoyl-CoA hydratase-lyase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 2VSS | Wild-type Hydroxycinnamoyl-CoA hydratase lyase in complex with acetyl- CoA and vanillin | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2VSS | Wild-type hydroxycinnamoyl-CoA hydratase lyase in complex with acetyl- CoA and vanillin | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2VSU | A ternary complex of Hydroxycinnamoyl-CoA Hydratase-Lyase (HCHL) with acetyl-Coenzyme A and… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2VSU | A ternary complex of hydroxycinnamoyl-CoA hydratase-lyase (hchl) with acetyl-coenzyme a and… | x-ray diffraction | A, B, C, D, E, F | — | — |
| O69762 | AlphaFold monomer V2.0 prediction for hydroxycinnamoyl-CoA hydratase- lyase (O69762) | predicted | A | — | 3 (best 0.57) |
Experiment against prediction
- 2VSS chain D against the predicted model O69762: TM-score 0.99, RMSD 0.52 Å
- 2VSS chain D against the predicted model O69762: TM-score 0.99, RMSD 0.52 Å
- 2VSU chain D against the predicted model O69762: TM-score 0.99, RMSD 0.54 Å
- 2VSU chain D against the predicted model O69762: TM-score 0.99, RMSD 0.54 Å
- 2VSU chain A against the predicted model O69762: TM-score 0.99, RMSD 0.54 Å
- 2VSU chain A against the predicted model O69762: TM-score 0.99, RMSD 0.54 Å
- 2VSU chain F against the predicted model O69762: TM-score 0.99, RMSD 0.55 Å
- 2VSU chain F against the predicted model O69762: TM-score 0.99, RMSD 0.55 Å
- 2VSS chain F against the predicted model O69762: TM-score 0.99, RMSD 0.55 Å
- 2VSS chain F against the predicted model O69762: TM-score 0.99, RMSD 0.55 Å
Elsewhere
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