UniProt O67035

RNA-free ribonuclease P (O67035)

RNA-free ribonuclease P (UniProt O67035), EC 3.1.26.5: 3 experimental structures and 1 predicted model on GenesisL1, 38 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: O67035
Protein: RNA-free ribonuclease P
EC: 3.1.26.5
Experimental structures: 3
Predicted models: 1
Pockets: 38 · 2 records with a druggable one

Structures

4 records of O67035 in the MolNFT archive: 3 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
7F3E	Cryo-EM structure of the minimal protein-only RNase P from Aquifex aeolicus	electron microscopy	E, F, C, D, A, B, H, G, J, I, L, K	—	20 (best 0.68)
7F3E	Cryo-EM structure of the minimal protein-only RNase P from aquifex aeolicus	electron microscopy	E, F, C, D, A, B, H, G, J, I, L, K	—	—
8KD9	Cryo-EM structure of Aquifex aeolicus minimal protein-only RNase P (HARP) in complex with pre-tRNAs	electron microscopy	A, B, C, D, E, F, G, H, I, J, K, L	—	18 (best 0.81)
O67035	AlphaFold monomer V2.0 prediction for RNA-free ribonuclease P (O67035)	predicted	A	—	—

Experiment against prediction

8KD9 chain K against the predicted model O67035: TM-score 0.92, RMSD 1.61 Å
8KD9 chain B against the predicted model O67035: TM-score 0.91, RMSD 1.69 Å
8KD9 chain D against the predicted model O67035: TM-score 0.90, RMSD 1.97 Å
8KD9 chain I against the predicted model O67035: TM-score 0.89, RMSD 2.03 Å
7F3E chain H against the predicted model O67035: TM-score 0.89, RMSD 2.01 Å
7F3E chain G against the predicted model O67035: TM-score 0.89, RMSD 2.01 Å
7F3E chain B against the predicted model O67035: TM-score 0.89, RMSD 2.01 Å
7F3E chain K against the predicted model O67035: TM-score 0.89, RMSD 2.01 Å
7F3E chain I against the predicted model O67035: TM-score 0.89, RMSD 2.01 Å
7F3E chain A against the predicted model O67035: TM-score 0.89, RMSD 2.01 Å

Elsewhere

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