UniProt O66592
Deoxyuridine 5'-triphosphate nucleotidohydrolase (O66592)
Deoxyuridine 5'-triphosphate nucleotidohydrolase (UniProt O66592), EC 3.6.1.23: 1 experimental structure and 1 predicted model on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, druggability and experiment against…
- UniProt
- O66592
- Protein
- Deoxyuridine 5'-triphosphate nucleotidohydrolase
- EC
- 3.6.1.23
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 4 · 1 record with a druggable one
Structures
2 records of O66592 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8Y1Q | Crystal structure of Aquifex aeolicus dUTPase complexed with dUMP. | x-ray diffraction | A, B, C | DU, MG | 4 (best 0.76) |
| O66592 | AlphaFold monomer V2.0 prediction for deoxyuridine 5'-triphosphate nucleotidohydrolase (O66592) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8Y1Q chain B against the predicted model O66592: TM-score 0.99, RMSD 0.51 Å
- 8Y1Q chain C against the predicted model O66592: TM-score 0.98, RMSD 0.55 Å
- 8Y1Q chain A against the predicted model O66592: TM-score 0.98, RMSD 0.66 Å
Elsewhere
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