UniProt O66496
2-dehydro-3-deoxyphosphooctonate aldolase (O66496)
2-dehydro-3-deoxyphosphooctonate aldolase (UniProt O66496): 66 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O66496
- Protein
- 2-dehydro-3-deoxyphosphooctonate aldolase
- Experimental structures
- 66
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
67 records of O66496 in the MolNFT archive: 66 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FWN | Aquifex aeolicus KDO8P synthase in complex with pep | x-ray diffraction | A, B | — | — |
| 1FWN | Aquifex aeolicus KDO8P synthase in complex with pep | x-ray diffraction | A, B | — | — |
| 1FWS | Aquifex aeolicus KDO8P synthase in complex with pep and cadmium | x-ray diffraction | A, B | — | — |
| 1FWS | Aquifex aeolicus KDO8P synthase in complex with pep and cadmium | x-ray diffraction | A, B | — | — |
| 1FWT | Aquifex aeolicus KDO8P synthase in complex with pep, E4P and cadmium | x-ray diffraction | A, B | — | — |
| 1FWT | Aquifex aeolicus KDO8P synthase in complex with pep, E4P and cadmium | x-ray diffraction | A, B | — | — |
| 1FWW | Aquifex aeolicus KDO8P synthase in complex with pep, A5P and cadmium | x-ray diffraction | A, B | — | — |
| 1FWW | Aquifex aeolicus KDO8P synthase in complex with pep, A5P and cadmium | x-ray diffraction | A, B | — | — |
| 1FX6 | Aquifex aeolicus KDO8P synthase | x-ray diffraction | A, B | — | — |
| 1FX6 | Aquifex aeolicus KDO8P synthase | x-ray diffraction | A, B | — | — |
| 1FXP | Aquifex aeolicus KDO8P synthase in complex with cadmium | x-ray diffraction | A, B | — | — |
| 1FXP | Aquifex aeolicus KDO8P synthase in complex with cadmium | x-ray diffraction | A, B | — | — |
| 1FXQ | Aquifex aeolicus KDO8P synthase in complex with pep and A5P | x-ray diffraction | A, B | — | — |
| 1FXQ | Aquifex aeolicus KDO8P synthase in complex with pep and A5P | x-ray diffraction | A, B | — | — |
| 1FY6 | Aquifex aeolicus KDO8P synthase in complex with cadmium and A5P | x-ray diffraction | A, B | — | — |
| 1FY6 | Aquifex aeolicus KDO8P synthase in complex with cadmium and A5P | x-ray diffraction | A, B | — | — |
| 1JCX | Aquifex aeolicus KDO8P synthase in complex with API and Cadmium | x-ray diffraction | A, B | — | — |
| 1JCX | Aquifex aeolicus KDO8P synthase in complex with api and cadmium | x-ray diffraction | A, B | — | — |
| 1JCY | Aquifex aeolicus KDO8P synthase in complex with R5P, PEP and Cadmium | x-ray diffraction | A, B | — | — |
| 1JCY | Aquifex aeolicus KDO8P synthase in complex with R5P, pep and cadmium | x-ray diffraction | A, B | — | — |
| 1LRN | Aquifex aeolicus KDO8P synthase H185G mutant in complex with Cadmium | x-ray diffraction | A, B | — | — |
| 1LRN | Aquifex aeolicus KDO8P synthase H185G mutant in complex with cadmium | x-ray diffraction | A, B | — | — |
| 1LRO | Aquifex aeolicus KDO8P synthase H185G mutant in complex with PEP and Cadmium | x-ray diffraction | A, B | — | — |
| 1LRO | Aquifex aeolicus KDO8P synthase H185G mutant in complex with pep and cadmium | x-ray diffraction | A, B | — | — |
| 1LRQ | Aquifex aeolicus KDO8P synthase H185G mutant in complex with PEP, A5P and Cadmium | x-ray diffraction | A, B | — | — |
| 1LRQ | Aquifex aeolicus KDO8P synthase H185G mutant in complex with pep, A5P and cadmium | x-ray diffraction | A, B | — | — |
| 1PCK | Aquifex aeolicus KDO8PS in complex with Z-methyl-PEP | x-ray diffraction | A, B | — | — |
| 1PCK | Aquifex aeolicus KDO8PS in complex with Z-methyl-pep | x-ray diffraction | A, B | — | — |
| 1PCW | Aquifex aeolicus KDO8PS in complex with cadmium and APP, a bisubstrate inhibitor | x-ray diffraction | A, B | — | — |
| 1PCW | Aquifex aeolicus KDO8PS in complex with cadmium and app, a bisubstrate inhibitor | x-ray diffraction | A, B | — | — |
| 1PE1 | Aquifex aeolicus KDO8PS in complex with cadmium and 2-PGA | x-ray diffraction | A, B | — | — |
| 1PE1 | Aquifex aeolicus KDO8PS in complex with cadmium and 2-pga | x-ray diffraction | A, B | — | — |
| 1T8X | r106g kdo8ps with pep and a5p | x-ray diffraction | A, B | — | — |
| 1T8X | R106G KDO8PS with pep and A5P | x-ray diffraction | A, B | — | — |
| 1T96 | r106g kdo8ps with pep | x-ray diffraction | A, B | — | — |
| 1T96 | R106G KDO8PS with pep | x-ray diffraction | A, B | — | — |
| 1T99 | r106g kdo8ps without substrates | x-ray diffraction | A, B | — | — |
| 1T99 | R106G KDO8PS without substrates | x-ray diffraction | A, B | — | — |
| 1ZHA | A. aeolicus KDO8PS R106G mutant in complex with PEP and R5P | x-ray diffraction | A, B | — | — |
| 1ZHA | A. aeolicus KDO8PS R106G mutant in complex with pep and R5P | x-ray diffraction | A, B | — | — |
| 1ZJI | Aquifex aeolicus KDO8PS R106G mutant in complex with 2PGA and R5P | x-ray diffraction | A, B | — | — |
| 1ZJI | Aquifex aeolicus KDO8PS R106G mutant in complex with 2PGA and R5P | x-ray diffraction | A, B | — | — |
| 2A21 | Aquifex aeolicus KDO8PS in complex with PEP, PO4, and Zn2+ | x-ray diffraction | A, B | — | — |
| 2A21 | Aquifex aeolicus KDO8PS in complex with pep, PO4, and ZN2+ | x-ray diffraction | A, B | — | — |
| 2A2I | Aquifex aeolicus KDO8PS in complex with PEP, A5P, Zn2+ | x-ray diffraction | A, B | — | — |
| 2A2I | Aquifex aeolicus KDO8PS in complex with pep, A5P, ZN2+ | x-ray diffraction | A, B | — | — |
| 2EF9 | Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P… | x-ray diffraction | A, B | — | — |
| 2EF9 | Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P… | x-ray diffraction | A, B | — | — |
| 2NWR | Crystal structure of C11N mutant of KDO8P Synthase in complex with PEP | x-ray diffraction | A, B | — | — |
| 2NWR | Crystal structure of C11N mutant of KDO8P synthase in complex with pep | x-ray diffraction | A, B | — | — |
| 2NWS | Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P… | x-ray diffraction | A, B | — | — |
| 2NWS | Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P… | x-ray diffraction | A, B | — | — |
| 2NX1 | Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P… | x-ray diffraction | A, B | — | — |
| 2NX1 | Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P… | x-ray diffraction | A, B | — | — |
| 2NX3 | Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 2NX3 | Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 2NXG | Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P… | x-ray diffraction | A, B | — | — |
| 2NXG | Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P… | x-ray diffraction | A, B | — | — |
| 2NXH | Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 2NXH | Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
7 records more on the page itself.
Experiment against prediction
- 1JCY chain A against the predicted model O66496: TM-score 1.00, RMSD 0.18 Å
- 1JCY chain A against the predicted model O66496: TM-score 1.00, RMSD 0.18 Å
- 1FWT chain A against the predicted model O66496: TM-score 1.00, RMSD 0.18 Å
- 1FWT chain A against the predicted model O66496: TM-score 1.00, RMSD 0.18 Å
- 1FWW chain A against the predicted model O66496: TM-score 1.00, RMSD 0.18 Å
- 1FWW chain A against the predicted model O66496: TM-score 1.00, RMSD 0.18 Å
- 2A21 chain B against the predicted model O66496: TM-score 1.00, RMSD 0.18 Å
- 1FWT chain B against the predicted model O66496: TM-score 1.00, RMSD 0.18 Å
- 1FWT chain B against the predicted model O66496: TM-score 1.00, RMSD 0.18 Å
- 1FXQ chain B against the predicted model O66496: TM-score 1.00, RMSD 0.19 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.